An exploratory study of adherence to topical benzoyl peroxide in patients with acne vulgaris

Yentzer, Brad A.; Alikhan, Ali; Teuschler, Hoa; Williams, Lisa L.; Tusa, Mark G.; Fleischer, Alan B.; Kaur, Mandeep; Balkrishnan, Rajesh; Feldman, Steven R.

doi:10.1016/j.jaad.2008.11.019

Cited by 35 publications

(36 citation statements)

References 6 publications

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“…Other studies utilizing questionnaires and/or single questions to assess adherence have found rates of poor adherence ranging from 76 to 0% [2,3,5,15,16,17]. Studies using objective measures such as not keeping appointments, pill counts, weighing medication, number of medication refills, and electronic caps have reported adherence rates ranging from 28 to 88.3% [6,7,8,18]. Clearly, more study is needed to fully understand adherence rates; however, it seems reasonable for clinicians to expect that approximately half of their patients may fail to follow prescribing instructions.…”

Section: Discussionmentioning

confidence: 99%

“…Some studies have evaluated adherence to acne medications in various parts of the world [2,3,4,5,6,7,8]; however, there are few data specific to Japan. This study was designed to assess adherence among acne patients in Japan, to determine if there are differences in adherence based on type of treatment (topical or oral), and to evaluate the factors that can affect adherence to acne treatment.…”

Section: Introductionmentioning

confidence: 99%

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Acne Management in Japan: Study of Patient Adherence

et al. 2011

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Obtaining good adherence to acne therapy is a challenge for all dermatologists. We studied 428 acne patients in Japan to determine the likelihood of good adherence and factors associated with medication-taking. This study utilized a simple validated questionnaire to assess risk of poor adherence; information about patient and treatment characteristics was also collected. There was an overall rate of poor adherence in 76% of subjects. Adherence to topical medication was poor in 52% of those treated with a topical agent only (n = 123). Among those taking combination therapies (n = 275), adherence to the topical portion of therapy was poor in 49% of subjects. The likelihood of poor adherence to oral medication was higher, both when administered alone (n = 30, 93% poor adherence) and when given as part of a combination regimen (n = 275, 86%). Factors with an impact on adherence included satisfaction with treatment (p = 0.023) and the experience of side effects (p = 0.027). Patients who felt they had a good understanding of acne and its treatment were more likely to have good adherence. These data suggest that there is significant room for improvement in acne adherence in Japan, as in other areas of the world, and that improved education may enhance adherence.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Acne Management in Japan: Study of Patient Adherence

et al. 2011

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“…Better medication adherence improves patient outcomes and has the potential to reduce healthcare costs by preventing unnecessary hospitalizations (6). Poor adherence is a particular challenge in the field of dermatology, given the preponderance of chronic diseases and messy, inconvenient topical medications that are the mainstay of therapy in dermatological diseases (7,8).…”

Section: Introductionmentioning

confidence: 99%

How often do pharmacology textbooks address medication adherence?

Farhangian¹,

Barnes²,

Huang³

et al. 2015

Journal of Dermatological Treatment

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“…Ein Review zu dem Thema von Park et al [5] ergab hingegen vor allem die Häufigkeit der Konsultationen als positiven Einfluss zur Verbesserung der Akne-Compliance, wäh-rend ein täglicher Anruf beispielsweise kaum einen Effekt hatte. Auch eine Erinnerung durch die Eltern scheint so gut wie keinen oder sogar negative Effekte auf die Therapieanwendung zu haben [6]. Um festzustellen, ob die tägliche Erinnerung durch SMS bei 14-28-jährigen Patienten einen Unterschied in Bezug auf die Therapietreue macht, wurden in der hier vorgestellten Studie 160 Akne-Patienten randomisiert und prospektiv untersucht; dabei erhielt die Kontrollgruppe keine Erinnerungen.…”

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Acne Smart Club: Ein Patientenschulungsprogramm für Menschen mit Akne

Park¹,

Nishiwaki²,

Kabashima³

et al. 2015

Kompass Dermatol

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Ziel: Beurteilung der Therapietreue von Aknepatienten, die mittels Mobiltelefon und Kurznachrichten (SMS) kommunizieren.Methoden: 160 Patienten wurden per Randomisierung auf 2 Gruppen verteilt: Die SMS-Gruppe erhielt über einen Zeitraum von 12 Wochen 2-mal täglich je 1 Kurznachricht; die Kontrollgruppe erhielt keine solchen Nachrichten. Vor und nach den 12 Wochen wurden die folgenden Evaluationsmaßnahmen bei allen Patienten durchgeführt: digitale Fotos, das Global Acne Grading System, der Dermatology Life Quality Index, der Cardiff Acne Disability Index, eine Beurteilung des Arzt-Patienten-Verhältnisses mittels der Patient-Doctor Depth-of-Relationship Scale sowie eine Beurteilung der Adhärenz, indem die Patienten gefragt wurden, an wie vielen Tagen pro Woche sie die Therapievorschriften eingehalten hatten. Die statistische Auswertung erfolgte mittels Student-t-Test.Ergebnisse: Bei der SMS-Gruppe hatten sich alle Parameter deutlicher verbessert als bei der Kontrollgruppe.Schlussfolgerung: Adhärenz und Compliance sind höher, wenn die Patienten in eine Kontrollstrategie eingebunden sind.Übersetzung aus Dermatology 2014;229:136-140 (DOI: 10.1159/000362809)

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An exploratory study of adherence to topical benzoyl peroxide in patients with acne vulgaris

Cited by 35 publications

References 6 publications

Acne Management in Japan: Study of Patient Adherence

Acne Management in Japan: Study of Patient Adherence

How often do pharmacology textbooks address medication adherence?

Acne Smart Club: Ein Patientenschulungsprogramm für Menschen mit Akne

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