An ICT-based organic framework for the fluorogenic detection of lethal pulmonary agent phosgene

Mondal, Tapan Kumar; Biswas, Amitav; Maji, Atanu; Gharami, Saswati

doi:10.1039/d3nj02580b

Cited by 5 publications

(1 citation statement)

References 62 publications

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“…The phosgene process is the current industrial method for isocyanate production. However, phosgene, a highly toxic gas, poses environmental and health risks. − Consequently, substantial research endeavors are dedicated to devising new isocyanate production methods. This review discusses isocyanate preparation techniques, including the phosgene and nonphosgene methods.…”

Section: Introductionmentioning

confidence: 99%

How To Get Isocyanate?

Guo,

Ding,

Wang

2024

ACS Omega

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Isocyanate, a pivotal chemical intermediate to synthesize polyurethane with widespread applications in household appliances, automobiles, and construction, is predominantly produced via the phosgene process, which currently holds a paramount status in industrial isocyanate production. Nonetheless, concerns arise from the toxicity of phosgene and the corrosiveness of hydrogen chloride, posing safety hazards. The synthesis of isocyanate using nonphosgene methods represents a promising avenue for future development. This article primarily focuses on the nonphosgene approach, which involves the formation of carbamate through the reaction of nitro-amino compounds with carbon monoxide, dimethyl carbonate, and urea, among other reagents, subsequently leading to the thermal decomposition of carbamate to get isocyanate. This paper emphasizes the progress in catalyst development during the carbamate decomposition process. Single-component metal catalysts, particularly zinc, exhibit advantages such as high activity, cost-effectiveness, and compatibility with a wide range of substrates. Composite catalysts enhance isocyanate yield by introducing a second component to adjust the active metal composition. The central research direction aims to optimize catalyst adaptation to reaction conditions, including temperature, pressure, time, and solvent, to achieve high raw material conversion and product yield.

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Section: Introductionmentioning

confidence: 99%