2023
DOI: 10.1002/bdr2.2229
|View full text |Cite
|
Sign up to set email alerts
|

An improved multicellular human organoid model for the study of chemical effects on palatal fusion

Cynthia J. Wolf,
Hunter Fitzpatrick,
Carrie Becker
et al.

Abstract: BackgroundTissue fusion is a mechanism involved in the development of the heart, iris, genital tubercle, neural tube, and palate during embryogenesis. Failed fusion of the palatal shelves could result in cleft palate (CP), a common birth defect. Organotypic models constructed of human cells offer an opportunity to investigate developmental processes in the human. Previously, our laboratory developed an organoid model of the human palate that contains human mesenchyme and epithelial progenitor cells to study th… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 58 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?