An incidental nonfunctioning mediastinal paragaglioma (2009: 11b)

Abstract

A rare case of an incidental nonfunctioning mediastinal paraganglioma is presented. The diagnosis of aorticosympathetic paraganglioma was established by histological examination after surgical removal of the tumor. The appearance of this rare tumor on multidetector coronary angiography is demonstrated and the differential diagnosis is discussed.

Successful resection of a huge paraganglioma utilizing cardiopulmonary bypass

“…Positron-emission tomography has been used but its value is not well established, especially considering cost and availability. 2 Mediastinal paragangliomas are accompanied by other synchronous paragangliomas in 10% of cases. 5 Fine needle aspiration is diagnostic especially when supported by immunohistochemistry, but the risk of bleeding might preclude this approach.…”

“…6 Magnetic resonance imaging is helpful in addressing the location and planning the management. 2 A metaiodobenzylguanidine scan is required to diagnose any other tumor foci in the body. Positron-emission tomography has been used but its value is not well established, especially considering cost and availability.…”

“…5 Fine needle aspiration is diagnostic especially when supported by immunohistochemistry, but the risk of bleeding might preclude this approach. 2 These tumors can be part of Carney's triad (pulmonary chondromas, gastrointestinal stromal tumor) or due to familial disorders. 5 Malignancy is based on distant metastasis or vascular invasion, and ranges from 21% to 76%.…”

“…They usually affect the older age groups, with a tendency to be asymptomatic. 2 Several diagnostic laboratory and radiological modalities are available to ascertain the diagnosis, location, functional status of the tumor, vascularity, and metastasis. Surgery is the mainstay of treatment, with the aim of achieving complete resection.…”