An innovative approach for separation and purification of natural products using carbon nanotube–alginate gel beads as a novel stationary phase

Long, Jingjing; Wang, Yuan; Xu, Yanan; Xu, Lixin

doi:10.1039/c4ra12732c

Cited by 3 publications

(3 citation statements)

References 24 publications

(18 reference statements)

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“…The application of SWCNTs and MWCNTs has also been extended to include achiral separation of a mixture of pharmaceuticals; an essential step in quantitative and qualitative analysis [ 130 , 131 ]. Several examples with promising outcomes have been reported where SWCNTs and MWCNTs were tested for their abilities to achieve achiral separations ( Table 2 ) [ 49 , 50 , 52 , 53 , 76 ].…”

Section: Swcnts and Mwcnts For Achiral Separation Of Pharmaceuticamentioning

confidence: 99%

Application of Carbon Nanotubes in Chiral and Achiral Separations of Pharmaceuticals, Biologics and Chemicals

et al. 2017

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Carbon nanotubes (CNTs) possess unique mechanical, physical, electrical and absorbability properties coupled with their nanometer dimensional scale that renders them extremely valuable for applications in many fields including nanotechnology and chromatographic separation. The aim of this review is to provide an updated overview about the applications of CNTs in chiral and achiral separations of pharmaceuticals, biologics and chemicals. Chiral single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) have been directly applied for the enantioseparation of pharmaceuticals and biologicals by using them as stationary or pseudostationary phases in chromatographic separation techniques such as high-performance liquid chromatography (HPLC), capillary electrophoresis (CE) and gas chromatography (GC). Achiral MWCNTs have been used for achiral separations as efficient sorbent objects in solid-phase extraction techniques of biochemicals and drugs. Achiral SWCNTs have been applied in achiral separation of biological samples. Achiral SWCNTs and MWCNTs have been also successfully used to separate achiral mixtures of pharmaceuticals and chemicals. Collectively, functionalized CNTs have been indirectly applied in separation science by enhancing the enantioseparation of different chiral selectors whereas non-functionalized CNTs have shown efficient capabilities for chiral separations by using techniques such as encapsulation or immobilization in polymer monolithic columns.

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Section: Swcnts and Mwcnts For Achiral Separation Of Pharmaceuticamentioning

confidence: 99%

Application of Carbon Nanotubes in Chiral and Achiral Separations of Pharmaceuticals, Biologics and Chemicals

et al. 2017

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show abstract

“…The application of SWCNTs and MWCNTs has also been extended to include achiral separation of a mixture of pharmaceuticals; an essential step in quantitative and qualitative analysis [129,130]. Several examples with promising outcomes have been reported where SWCNTs and MWCNTs were tested for their abilities to achieve achiral separations (Table 2) [49,50,52,53,76].…”

Section: Swcnts and Mwcnts For Achiral Separation Of Pharmaceuticals mentioning

confidence: 99%

“…Aniline compounds are important precursors in the synthesis of many chemicals, and hence the final purification from aniline derivatives is required for the purification of synthesized products. SWCNTs-alginate gel beads were synthesized as a stationary phase in HPLC and showed efficient separation and purification of natural products such as alkaloids [171]. The following two sections discuss the use of CNTs in achiral separation for the chromatographic purification purposes as one of their potential applications.…”

Section: Swcnts For Achiral Separation In Purificationmentioning

confidence: 99%

Application of Carbon Nanotubes in Chiral and Achiral Separations of Pharmaceuticals, Biologics and Chemicals

Hemasa

Naumovski

Maher

et al. 2017

Preprint

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Carbon nanotubes (CNTs) possess unique mechanical, physical, electrical and absorbability properties coupled with their nanometer dimensional scale that renders them extremely valuable for applications in many fields including nanotechnology and chromatographic separation. The aim of this review is to provide an updated overview about the applications of CNTs in chiral and achiral separations of pharmaceuticals, biologics and chemicals. Chiral SWCNTs and MWCNTs have been directly applied for the enantioseparation of pharmaceuticals and biologicals by using them as stationary or pseudostationary phases in chromatographic separation techniques such as high-performance liquid chromatography (HPLC), capillary electrophoresis (CE) and gas chromatography (GC). Achiral MWCNTs have been used for achiral separations as efficient sorbent objects in solid-phase extraction techniques of biochemicals and drugs. Achiral SWCNTs have been applied in achiral separation of biological samples. Achiral SWCNTs and MWCNTs have been also successfully used to separate achiral mixtures of pharmaceuticals and chemicals. Collectively, functionalized CNTs have been indirectly applied in separation science by enhancing the enantioseparation of different chiral selectors whereas, non-functionalized CNTs have shown efficient capabilities for chiral separations by using techniques such as encapsulation or immobilization in polymer monolithic columns.

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Porous carboxylated carbon nanotubes hydrogel microspheres for removing U(VI) from aqueous solutions

Jian

Xie

Duan

et al. 2023

J Radioanal Nucl Chem

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An innovative approach for separation and purification of natural products using carbon nanotube–alginate gel beads as a novel stationary phase

Abstract: A new packing material is studied in preparative or semi-preparative liquid chromatography with high separation efficiency and quality.

Cited by 3 publications

References 24 publications

Application of Carbon Nanotubes in Chiral and Achiral Separations of Pharmaceuticals, Biologics and Chemicals

Application of Carbon Nanotubes in Chiral and Achiral Separations of Pharmaceuticals, Biologics and Chemicals

Application of Carbon Nanotubes in Chiral and Achiral Separations of Pharmaceuticals, Biologics and Chemicals

Porous carboxylated carbon nanotubes hydrogel microspheres for removing U(VI) from aqueous solutions

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