An integrated biorefinery process for co-production of xylose and glucose using maleic acid as efficient catalyst

Liu, Zhenghui; Shi, Enze; Feng, Mang; Jiang, Kankan

doi:10.1016/j.biortech.2021.124698

Cited by 24 publications

(8 citation statements)

References 41 publications

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“…In prior reports, MA has been shown to be a safe and environmentally friendly organic acid that can be employed for the pretreatment of lignocellulosic materials. As the furfural byproduct derived from xylose dehydration necessitates higher activation energy, MA pretreatment can also lower byproduct yields as compared to sulfuric acid pretreatment ( 23 ). MA is also classified as a food additive, and it can thus be used in the co-preparation of XOS for use in feed additives.…”

Section: Introductionmentioning

confidence: 99%

“…MA is also classified as a food additive, and it can thus be used in the co-preparation of XOS for use in feed additives. While MA has previously been reported in the context of monosaccharide preparation ( 23 – 26 ), few studies have explored its value in the context of XOS production. As such, in this study, MA was herein utilized to facilitate xylan hydrolysis as a means of generating XOS.…”

Section: Introductionmentioning

confidence: 99%

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Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy

Jiang

Huang

et al. 2022

Front. Nutr.

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Xylooligosaccharides (XOS) are functional feed additives that are attracting growing commercial interest owing to their excellent ability to modulate the composition of the gut microbiota. The acid hydrolysis-based processing of xylan-containing materials has been proposed to represent a cost-effective approach to XOS preparation, with organic acids being preferable in this context. As such, in the present study, maleic acid was selected as a mild, edible organic acid for use in the hydrolysis of xylan to produce XOS. A response surface methodology (RSM) approach with a central composite design was employed to optimize maleic acid-mediated XOS production, resulting in a yield of 50.3% following a 15 min treatment with 0.08% maleic acid at 168°C. Under these conditions, the desired XOS degree of polymerization (2-3) was successfully achieved, demonstrating the viability of this using a low acid dose and a high reaction temperature to expedite the production of desired functional products. Moreover, as maleic acid is a relatively stable carboxylic acid, it has the potential to be recycled. These results suggest that dilute maleic acid-based thermal treatment of corncob-derived xylan can achieve satisfactory XOS yields, highlighting a promising and cost-effective approach to XOS production.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy

Jiang

Huang

et al. 2022

Front. Nutr.

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“…Cinnarizide maleate is a novel calcium channel antagonist which blocks the entry of calcium ions into smooth muscle cells, dilates blood vessels at the lesion sites, increases blood flow volume, and improves cerebral metabolism. In addition, cinnarizide reduces the levels of inflammatory factors by inhibiting platelet aggregation [15][16][17].…”

Section: Discussionmentioning

confidence: 99%

Efficacy and prognosis following combined cinepazaide maleate/nimodipine therapy in cerebral vasospasm patients after hemorrhage

Wu¹,

Chen²,

Xiao³

et al. 2021

Trop. J. Pharm Res

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Purpose: To investigate the efficacy and prognosis following treatment of cerebral vasospasm (CVS) patients with a combination of cinnarizide maleate and nimodipine after subarachnoid hemorrhage (SAH).Methods: Eighty-eight patients with CVS after SAH were selected and divided into control group (CG) and study group (EG), each with 44 patients (n = 44). Patients in CG were treated with intravenous infusion of cinnarizide maleate, while those in EG received intravenous infusion of cinnarizide maleate together, and their clinical efficacy and prognosis were compared.Results: Compared with CG, total treatment effectiveness (response) in EG was significantly higher, while levels of inflammatory factors were lower (p < 0.05). Serum protein levels of S100 β and ET-1, and MCA blood flow velocity in EG were notably lower (p < 0.05), but GCS scores were highercompared with CG (p < 0.05). The NIHSS scores were lower and BI indices were higher in EG than in CG (p < 0.05).Conclusion: Treatment of CVS patients after SAH using a combination of cinnarizide maleate and nimodipine effectively reduces the levels of inflammatory factors, improves quality of prognosis, and relieves symptoms of CVS, when compared with administration of cinnarizide maleate only. Therefore, the combination treatment is recommended for the management of CVS after SAH.

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“…Accordingly, this leachate can be applied to the mixed treatment of mature landfill leachate. The addition of young leachate not only brings a large amount of bioavailable carbon, but also provides a dilution effect on refractory organic matter and reduces the hard‐to‐degrade nature of influent leachate in terms of organic matter removal to achieve the purpose of enhancing the wastewater treatment effect (Liu et al, 2021; Yang et al, 2020; Zheng et al, 2009). Nevertheless, the introduction of ultra‐high concentrations of chloride ions in young leachate can impact microorganisms in biological treatment systems.…”

Section: Introductionmentioning

confidence: 99%

Microbial community response of the full‐scale MBR system for mixed leachates treatment

Song

et al. 2022

Water Environment Research

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In practice, mature landfill leachate and incineration (young) leachate are mixed to improve the biodegradability and enhance biological treatment performance. However, the ratio of mature‐to‐young leachates greatly influences MBR treatment efficiency and microbial community structure. This study investigated the treatment efficiency and microbial community structure of full‐scale MBR systems operated under two mix ratios, mature leachate: young leachate = 7:3 (v/v, denoted as LL) and 3:7 (v/v, denoted as IL). LL group showed lower Cl− and COD concentrations but a higher aromatic organic content comparing to IL group, and the COD and UV254 removals for LL were significantly lower than those for IL by MBR treatment. Microbial community structures were similar in both groups at phylum level, with dominant phyla being Proteobacteria (23.8%–32.3%), Bacteroidetes (15.25%–20.7%), Chloroflexi (10.5%–23.1%), and Patescibacteria (9.9%–13.2%). However, the richness and diversity of LL group were lower, and differences were observed at lower taxonomy levels. Results indicated that salinity mainly changed the structure of microbial community, resulting in greater abundance of salt‐tolerant microbials, while refractory organics affected microbial community structure, and also led to decreased diversity and metabolic activity. Therefore, in mixed leachates biological treatment, a higher young leachate ratio is recommended for better organics removal performance. Practitioner Points The trade‐off between refractory organics and salinity in mixed leachate treatment should be paid attention. Refractory organics reduced alpha and functional diversities of microorganisms. Mixed leachate with a higher young leachate ratio reached a better organic removal.

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An integrated biorefinery process for co-production of xylose and glucose using maleic acid as efficient catalyst

Cited by 24 publications

References 41 publications

Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy

Production of Prebiotic Xylooligosaccharides via Dilute Maleic Acid-Mediated Xylan Hydrolysis Using an RSM-Model-Based Optimization Strategy

Efficacy and prognosis following combined cinepazaide maleate/nimodipine therapy in cerebral vasospasm patients after hemorrhage

Microbial community response of the full‐scale MBR system for mixed leachates treatment

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