“…For example, N-Oleoyl-glycine is a lipid mediator that belongs to endocannabinoidome, which has recently gained attention for its protective effects in a mouse model of mild traumatic brain injury (Shahen-Zoabi et al, 2022 ). Besides, recent studies have also indicated an interaction between orexinergic and ECS, such as in addiction and fear (Deli et al, 2022 ; Ten-Blanco et al, 2022 ), while orexin's role in stress regulation and memory remains to be elucidated.…”