An intriguing future is approaching: Artificial intelligence meets molecularly imprinted polymers

Karasu, Tunca; Çalışır, Fatih; Pişkin, Sena; Özgür, Erdoğan; Armutcu, Canan; Çorman, Mehmet Emin; Uzun, Lokman

doi:10.1016/j.jpbao.2024.100041

Journal of Pharmaceutical and Biomedical Analysis Open

2024

DOI: 10.1016/j.jpbao.2024.100041

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An intriguing future is approaching: Artificial intelligence meets molecularly imprinted polymers

Tunca Karasu,

Fatih Çalışır,

Sena Pişkin

et al.

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Cited by 2 publications

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A Review Study on Molecularly Imprinting Surface Plasmon Resonance Sensors for Food Analysis

Bankoğlu Yola,

Özdemir,

Yola

2024

Biosensors

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Surface plasmon resonance (SPR) sensors have emerged as a powerful tool in biosensing applications due to their ability to provide sensitive and real-time detection of chemical and biological analytes. This review focuses on the development and application of molecularly imprinted polymer (MIP)-based SPR sensors for food analysis. By combining the high selectivity of molecular imprinting techniques with the sensitivity of SPR, these sensors offer significant advantages in detecting food contaminants and other target molecules. The article covers the basic principles of SPR, the role of MIPs in sensor specificity, recent advancements in this sensor development, and food applications. Furthermore, the potential for these sensors to contribute to food safety and quality control was explored, showcasing their adaptability to complex food matrices. The review concluded the future directions and challenges of SPR-MIP sensors in food analysis, emphasizing their promise in achieving high-throughput, cost-effective, and portable sensing solutions.

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A Review Study on Molecularly Imprinting Surface Plasmon Resonance Sensors for Food Analysis

Bankoğlu Yola,

Özdemir,

Yola

2024

Biosensors

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Computer-Assisted Strategies as a Tool for Designing Green Monomer-Based Molecularly Imprinted Materials

Sobiech

2024

IJMS

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Molecularly imprinted polymers (MIPs) are defined as artificial receptors due to their selectivity and specificity. Their advantageous properties compared to biological alternatives have sparked interest among scientists, as detailed in numerous review papers. Currently, there is significant attention on adhering to the principles of green chemistry and environmental protection. In this context, MIP research groups have focused on developing eco-friendly procedures. The application of “greener” monomers and reagents, along with the utilization of computational methodologies for design and property analysis, are two activities that align with the green chemistry principles for molecularly imprinted technology. This review discusses the application of computational methodologies in the preparation of MIPs based on eco-friendly non-acrylic/vinylic monomers and precursors, such as alkoxysilanes, ionic liquids, deep eutectic solvents, bio-based molecules—specifically saccharides, and biomolecules like proteins. It provides a brief introduction to MIP materials, the green aspects of MIP production, and the application of computational simulations. Following this, brief descriptions of the studied monomers, molecular simulation studies of green monomer-based MIPs, and computational strategies are presented. Finally, conclusions and an outlook on the future directions of computational analysis in the production of green imprinted materials are pointed out. To the best of my knowledge, this work is the first to combine these two aspects of MIP green chemistry principles.

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An intriguing future is approaching: Artificial intelligence meets molecularly imprinted polymers

Cited by 2 publications

References 139 publications

A Review Study on Molecularly Imprinting Surface Plasmon Resonance Sensors for Food Analysis

A Review Study on Molecularly Imprinting Surface Plasmon Resonance Sensors for Food Analysis

Computer-Assisted Strategies as a Tool for Designing Green Monomer-Based Molecularly Imprinted Materials

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