Supply chains are getting increasing substance but the antecedents of their failure and success are not clearly identified till yet. The main aim of this study is to examine the influence of Cultural Competitiveness (CC), Market Turbulence (MT), and Knowledge Development (KD) on the performance of cycle time. The conceptual framework is proposed based upon extensive literature review. For this study, data was collected from 91 respondent manufacturing organizations. Upon assuring the reliability and validity of the constructs, correlation and hierarchical regression were used to test the hypotheses. Findings reveal that CC and MT have positive impact on cycle time. KD has insignificant association with performance of cycle time. No joint relationship of CC and KD, MT and CC, and MT and KD was found affecting the performance of cycle time. Practically, it is difficult to achieve dramatic reorientation of supply chains, and it is less likely that the failure of the two elements (CC and MT) can be quickly remedied. Our results indicate that such businesses can benefit from building CC -with the focus on MT -it will ensure that the company has at least some of the advantages of reducing cycle time.