An isocratic solvent-free mobile phase HPLC-PDA analysis of clenbuterol and ractopamine

Furusawa, Naoto

doi:10.1016/j.ijcas.2013.07.002

Cited by 5 publications

(2 citation statements)

References 22 publications

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“…Currently, the detection techniques for LMP residues in animal feed and food include high-performance liquid chromatography (HPLC) [20,21], liquid chromatography-mass spectrometry (LC-MS) [22,23], gas chromatography-mass spectrometry (GC-MS) [24], ultrahigh-performance liquid chromatography (UHPLC) [25], and capillary electrophoresis (CE) [26], etc. Although the above methods have lower limits of detection and better stability, they have the disadvantages of long detection time, expensive instruments, and complicated operation.…”

Section: Introductionmentioning

confidence: 99%

Advance in Detection Technique of Lean Meat Powder Residues in Meat Using SERS: A Review

Guo,

Peng,

Qin

et al. 2023

Molecules

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Food that contains lean meat powder (LMP) can cause human health issues, such as nausea, headaches, and even death for consumers. Traditional methods for detecting LMP residues in meat are often time-consuming and complex and lack sensitivity. This article provides a review of the research progress on the use of surface–enhanced Raman spectroscopy (SERS) technology for detecting residues of LMP in meat. The review also discusses several applications of SERS technology for detecting residues of LMP in meat, including the enhanced detection of LMP residues in meat based on single metal nanoparticles, combining metal nanoparticles with adsorbent materials, combining metal nanoparticles with immunizing and other chemicals, and combining the SERS technology with related techniques. As SERS technology continues to develop and improve, it is expected to become an even more widely used and effective tool for detecting residues of LMP in meat.

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Section: Introductionmentioning

confidence: 99%

Advance in Detection Technique of Lean Meat Powder Residues in Meat Using SERS: A Review

Guo,

Peng,

Qin

et al. 2023

Molecules

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“…In order to ensure the safety of meat-based food products, regular screening, and monitoring of antibiotic residues are necessary. The chromatographic methods such as liquid chromatography-mass spectrometry (LC-MS) [5], high-performance liquid chromatography (HPLC) [6] and gas chromatography-mass spectrometry (GC-MS) [7] are reliable techniques to determine CLB in real samples. The complicated sample preparation steps must be performed by the skilled person to operate the chromatographic instruments, which will easily cause loss or reduce the amount of analyte during the extraction process and it results in inaccurate analysis.…”

Section: Introductionmentioning

confidence: 99%

Development of Highly Sensitive Immunosensor for Clenbuterol Detection by Using Poly(3,4-ethylenedioxythiophene)/Graphene Oxide Modified Screen-Printed Carbon Electrode

Talib

Salam

Sulaiman

2018

Sensors

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Clenbuterol (CLB) is an antibiotic and illegal growth promoter drug that has a long half-life and easily remains as residue and contaminates the animal-based food product that leads to various health problems. In this work, electrochemical immunosensor based on poly(3,4-ethylenedioxythiophene)/graphene oxide (PEDOT/GO) modified screen-printed carbon electrode (SPCE) for CLB detection was developed for antibiotic monitoring in a food product. The modification of SPCE with PEDOT/GO as a sensor platform was performed through electropolymerization, while the electrochemical assay was accomplished while using direct competitive format in which the free CLB and clenbuterol-horseradish peroxidase (CLB-HRP) in the solution will compete to form binding with the polyclonal anti-clenbuterol antibody (Ab) immobilized onto the modified electrode surface. A linear standard CLB calibration curve with R2 = 0.9619 and low limit of detection (0.196 ng mL−1) was reported. Analysis of milk samples indicated that this immunosensor was able to detect CLB in real samples and the results that were obtained were comparable with enzyme-linked immunosorbent assays (ELISA).

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Clenbuterol Hydrochloride

Al-Majed

Khalil

Khbrani

et al. 2017

Profiles of Drug Substances, Excipients and Related Methodology

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An isocratic solvent-free mobile phase HPLC-PDA analysis of clenbuterol and ractopamine

Cited by 5 publications

References 22 publications

Advance in Detection Technique of Lean Meat Powder Residues in Meat Using SERS: A Review

Advance in Detection Technique of Lean Meat Powder Residues in Meat Using SERS: A Review

Development of Highly Sensitive Immunosensor for Clenbuterol Detection by Using Poly(3,4-ethylenedioxythiophene)/Graphene Oxide Modified Screen-Printed Carbon Electrode

Clenbuterol Hydrochloride

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