An optical fiber-waveguide-fiber platform for ppt level evanescent field-based sensing

Wang, Yunkun; Tan, Bing; Liu, Shurong; Tian, Tian; Xu, Gongjie; Cai, Bin

doi:10.1016/j.snb.2019.127548

Cited by 14 publications

(9 citation statements)

References 28 publications

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“…In addition, CdZnSeS-pATP QDs could be used as fluorescence probes to detect the total acidity of paper-based relics in a nondestructive way by using optical fibers [ 59 ]. To the best of our knowledge, this is a nondestructive fluorescence assay based on QDs to measure the total acidity of paper-based relics for the first time.…”

Section: Discussionmentioning

confidence: 99%

Quaternary Alloy Quantum Dots as Fluorescence Probes for Total Acidity Detection of Paper-Based Relics

Wang

Cheng

et al. 2021

Nanomaterials

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Traditionally, the acidity of paper-based relics was determined by an extraction method and using a pH meter. This method could not obtain the total acidity of the paper-based relics because it only detected the concentration of free protons in the aqueous soaking solution. To overcome this defect, a new method for determining the total acidity of paper-based relics has been established by using quaternary alloy quantum dots. The quantum dots, CdZnSeS, modified by p-Aminothiophenol (pATP) were prepared, and their composition and structure were characterized. The fluorescence behavior of prepared quantum dots with acidity was investigated. The following results were obtained. The fluorescence of CdZnSeS-pATP quantum dots could decrease with increases in acidity because pATP dissociated from the surfaces of the quantum dots due to protons or undissociated weak acids. Based on this feature, a method for determining the acidity of paper-based relics was constructed, and this method was used to evaluate the acidity of actual paper-based relics. Obviously, for a given paper sample, since both free protons and bound protons can be determined by this method, the acidity measured by this method is more reasonable than that by pH meter.

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Section: Discussionmentioning

confidence: 99%

Quaternary Alloy Quantum Dots as Fluorescence Probes for Total Acidity Detection of Paper-Based Relics

Wang

Cheng

et al. 2021

Nanomaterials

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“…The length of the waveguide was easily tuned by adjusting the distance between the two optical fibers. The experimental details are the same as those in our previous study. , …”

Section: Methodsmentioning

confidence: 99%

“…To achieve high sensitivity, one of the fundamental issues is enhancing the interaction between the probe light and the MIP sensing interface. In our previous studies, we developed a serially grafted optical fiber–waveguide–fiber (OFWF) sensing system, which can efficiently utilize the EW of the noncladded waveguide as a sensing probe and realized a spectral LOD of ∼10 –12 g/mL in the detection of rhodamine B (Rh B) based on the fluorescence spectra . Moreover, to further enhance the probing EW, the waveguide was covered with a high-refractive index Ta 2 O 5 nanolayer, which dramatically increased the EW intensity of the waveguide by 2–3 orders of magnitude and afforded a LOD of ∼1.0 × 10 –15 g/mL in fluorescence sensing …”

Section: Introductionmentioning

confidence: 99%

Molecularly Imprinted Polymer-Coated Optical Waveguide for Attogram Sensing

Zhou

et al. 2022

ACS Appl. Mater. Interfaces

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Ultrahigh sensitivity and selectivity are the ultimate goals of sensor development. For such purposes, we propose a sensing platform in which an optical fiber–waveguide–fiber (OFWF) structure is integrated with a molecularly imprinted polymer (MIP). The OFWF works as a highly efficient probe light launcher and signal light collector, and the MIP layer acts as a highly selective and sensitive sensing interface. In the MIP design, a high-molecular refractive index monomer (2-phenylphenoxyethyl acrylate) was copolymerized with a MIP functional monomer (acrylic acid). The resulting high-refractive index MIP layers could effectively extract the probe light from the waveguide and send it to the MIP sensing interface. Moreover, a highly elastic cross-linker (poly(ethylene glycol) 600 diacrylate) was employed to increase the MIP mesh size, which could effectively increase the penetrability of the analyte. Rhodamine B (Rh B) is widely used in the textile industry, and its contamination may lead to serious public health problems. As a proof of concept, the Rh B chromophore was used as a molecular template, and the thin MIP layer was cured on the waveguide surface by utilizing the evanescent wave of the 405 nm propagating light in the waveguide. The MIP-OFWF sensing platform afforded highly selective monitoring of the absorption spectra of the components in a mixture solution of Rh B and methyl blue. It also afforded an extremely low detection limit of approximately 6.5 × 10–17 g/mL, with an absolute mass of 20–30 ag.

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“…A neoteric approach for sensitivity enhancement employed by Akhtar's group includes growing ZnO nanoflowers on a glass slide coated with silver nanofilm for ultrasensitive detection of insulin amyloid [178]. Sophisticated assemblies such as dual-colour TIR fluorescence detecting platform [179] as well as optical fibre-polymer waveguide-optical fibre sandwich [180] set up have facilitated small-molecule detection down to picomolar levels.…”

Section: Evanescent Wave-based Sensors For Biomedical Diagnosticsmentioning

confidence: 99%

“…Micromachines 2020, 11, x FOR PEER REVIEW 13 of 31 fluorescence detecting platform [179] as well as optical fibre-polymer waveguide-optical fibre sandwich [180] set up have facilitated small-molecule detection down to picomolar levels.…”

Section: Bioluminescence-based Sensors For Biomedical Diagnosticsmentioning

confidence: 99%

Recent Progress in Optical Sensors for Biomedical Diagnostics

Pirzada

Altıntaş

2020

Micromachines

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In recent years, several types of optical sensors have been probed for their aptitude in healthcare biosensing, making their applications in biomedical diagnostics a rapidly evolving subject. Optical sensors show versatility amongst different receptor types and even permit the integration of different detection mechanisms. Such conjugated sensing platforms facilitate the exploitation of their neoteric synergistic characteristics for sensor fabrication. This paper covers nearly 250 research articles since 2016 representing the emerging interest in rapid, reproducible and ultrasensitive assays in clinical analysis. Therefore, we present an elaborate review of biomedical diagnostics with the help of optical sensors working on varied principles such as surface plasmon resonance, localised surface plasmon resonance, evanescent wave fluorescence, bioluminescence and several others. These sensors are capable of investigating toxins, proteins, pathogens, disease biomarkers and whole cells in varied sensing media ranging from water to buffer to more complex environments such as serum, blood or urine. Hence, the recent trends discussed in this review hold enormous potential for the widespread use of optical sensors in early-stage disease prediction and point-of-care testing devices.

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An optical fiber-waveguide-fiber platform for ppt level evanescent field-based sensing

Cited by 14 publications

References 28 publications

Quaternary Alloy Quantum Dots as Fluorescence Probes for Total Acidity Detection of Paper-Based Relics

Quaternary Alloy Quantum Dots as Fluorescence Probes for Total Acidity Detection of Paper-Based Relics

Molecularly Imprinted Polymer-Coated Optical Waveguide for Attogram Sensing

Recent Progress in Optical Sensors for Biomedical Diagnostics

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