An Oral Supplementation Based on Hydrolyzed Collagen and Vitamins Improves Skin Elasticity and Dermis Echogenicity: A Clinical Placebo-Controlled Study

MBG, PatrAA­cia Maia Campos

doi:10.4172/2167-065x.1000142

Cited by 12 publications

(25 citation statements)

References 32 publications

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“…It is also important to highlight skin imaging techniques due to their importance for the analysis of morphological and structural characteristics of the skin. Equipment such as 20 mHz ultrasound (Dermacan ® ; Cortex, Hadsund, Denmark) allows the assessment of the ageing alterations by the analysis of thickness and echogenicity .…”

Section: Introductionmentioning

confidence: 99%

Photoageing‐related skin changes in different age groups: a clinical evaluation by biophysical and imaging techniques

Shirata

Alves

Campos

2019

Intern J of Cosmetic Sci

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Objectives In view of the lack of studies about the morphological and structural changes caused by solar radiation in young people, the aim of the present study was to evaluate the photoageing‐related changes in the skin of different age groups by biophysical and imaging techniques. Methods Forty‐four healthy female subjects were divided into two age groups: Group 1 (G1): 18–35 years old and Group 2 (G2): 40–60 years old. The skin of malar region of the face was evaluated in terms of mechanical properties, disorder in the pigmentation pattern, morphological and structural changes using the Cutometer®, Colorimeter®, Visioface® and Dermascan C® devices and reflectance confocal microscopy (Vivascope®). Results The results showed that the main changes in the skin of G1 were related to the pigmentation pattern, the papilla format and depletion of thin collagen fibres. These alterations were also observed in the skin of G2, but with more pronounced effects. Conclusion The knowledge about the skin changes caused by photoageing obtained in this study is very important for the development of dermocosmetic products for more effective treatments particularly focused on this type of skin. Finally, objective characterization of photoageing showed the importance of photoprotective habits since the first years of life in order to retard the appearance of skin changes caused by solar radiation.

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Section: Introductionmentioning

confidence: 99%

Photoageing‐related skin changes in different age groups: a clinical evaluation by biophysical and imaging techniques

Shirata

Alves

Campos

2019

Intern J of Cosmetic Sci

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“…This decrease of collagen in epithelial tissue is a result of the decreased fibroblasts metabolic activity, which are responsible for its synthesis. The structural support of the dermis tends to be lost during the aging process so, the skin becomes less elastic, thinner and this way, less able to resist to mechanical changes [29,30].…”

Section: Discussionmentioning

confidence: 99%

Clinical Efficacy of Dermocosmetic Formulations Containing Spirulina Extract on Young and Mature Skin: Effects on the Skin Hydrolipidic Barrier and Structural Properties

Sd¹,

Dg²,

Mm³

et al. 2015

Clin Pharmacol Biopharm

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Introduction: Spirulina is a unicellular blue-green alga rich in vitamins, minerals, pigments, proteins, polysaccharides, which indicates a high potential use in anti-aging cosmetic products as well as for skin protection. Preliminary studies showed antioxidant potential, immediate benefits on the skin microrelief and hydration and skin compatibility of formulations containing Spirulina extract. Thus, the objective of this study is to evaluate the long term clinical efficacy of dermocosmetic formulations containing Spirulina extract on young and mature skin using biophysical and skin imaging techniques.

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“…Sixty female subjects consumed either the supplement or placebo every day for 90 days (Campos et al . ). At the end of the trial, there was no significant difference in skin hydration between the treatment and placebo groups.…”

Section: Popular Nutraceutical Ingredients and Skin Ageingmentioning

confidence: 97%

“…Only one study reported a significant reduction in wrinkles, and a concomitant increase in collagen fibres was also found (Campos et al . ). Not all studies collected enough data to ascertain potential mechanisms of action ( e.g .…”

Section: Popular Nutraceutical Ingredients and Skin Ageingmentioning

confidence: 97%

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Nutraceuticals and skin appearance: Is there any evidence to support this growing trend?

Spiro

Lockyer

2018

Nutrition Bulletin

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The rise of the nutraceutical market, specifically oral nutrition supplements claiming to improve skin appearance, is striking. This paper aims to examine the published scientific evidence for beneficial effects of nutraceuticals on skin appearance. An overview of skin physiology and intrinsic and extrinsic ageing is provided which underlies the potential physiological processes nutraceuticals purport to counter. Common ingredients used are explored. Some of these (vitamins A, C, B2, B3, B7, copper, iodine, zinc) have authorised skin‐related health claims, but many do not. Current evidence for those without existing authorised claims (e.g. green tea extract, pomegranate extract, carotenoids, evening primrose oil, borage oil, fish oil, collagen and co‐enzyme Q10) is reviewed, focussing primarily on evidence from randomised controlled trials where available, in relation to skin parameters including wrinkles and hydration. Issues of safety are also considered, and the postulated mechanisms for some emerging ingredients, such as cocoa flavanols and probiotics, are explored. Evidence from high quality human trials demonstrating clear benefit is required by regulatory authorities in order for foods and nutrition supplements to carry a health or beauty claim. To date, the evidence for many ingredients in relation to skin appearance is limited, not sufficiently robust and/or inconsistent. Although there are a small number of human studies suggesting a potential benefit and some plausible biological mechanisms, much of the evidence to date comes from animal and in vitro studies. There are simply not enough good quality randomised controlled trials in this area to draw firm conclusions about the benefit of nutraceuticals to skin appearance.

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An Oral Supplementation Based on Hydrolyzed Collagen and Vitamins Improves Skin Elasticity and Dermis Echogenicity: A Clinical Placebo-Controlled Study

Cited by 12 publications

References 32 publications

Photoageing‐related skin changes in different age groups: a clinical evaluation by biophysical and imaging techniques

Photoageing‐related skin changes in different age groups: a clinical evaluation by biophysical and imaging techniques

Clinical Efficacy of Dermocosmetic Formulations Containing Spirulina Extract on Young and Mature Skin: Effects on the Skin Hydrolipidic Barrier and Structural Properties

Nutraceuticals and skin appearance: Is there any evidence to support this growing trend?

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