An Overview of Pelletization Techniques Used in Multiparticulate Drug Delivery System

Samreen, Mansoori

doi:10.20959/wjpr20178-9104

Cited by 2 publications

(2 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…31 Melt-granulates enable a slower medication release over longer timespan than standard granulation methods. Drug loading, processability, and overall repeatability may all be improved by combining lipid excipients with various melting points 32 .…”

Section: Melt Granulation/melt Pelletizationmentioning

confidence: 99%

A Concise review on application of solid lipids and various techniques in the formulation development

Ahire¹,

Kamble²

2023

J. Drug Delivery Ther.

View full text Add to dashboard Cite

Lipids have wide range of applications in food and pharmaceuticals. The pharmaceuticals application of lipid is to improve solubility of drug also helps to improve the bioavailability. The dissolution/dissolving phase, which is probably the rate-limiting component for oral absorption of poorly water-soluble drugs, is eliminated by pre-dissolving pharmaceuticals in lipids, surfactants, or combinations of lipid excipients and surfactants. The most widely used co-solvents, together with lipid excipients, are propylene glycol, glycerol, and polyethylene glycols-400, poloxamer etc. various technologies are used such as melt extrusion, melt granulation for preparation of lipid based oral modified released dosage forms. This review summaries the overview of the lipid excipients in terms of their classification, methods of absorption, and lipid-based product development. The manufacture of solid and semi-solid lipid formulations using various methodologies, applications, phase behaviour, and the regulatory outlook of lipid excipients are covered. Keywords: Solid lipids, lipid classification, solidification techniques, modified released.

show abstract

Section: Melt Granulation/melt Pelletizationmentioning

confidence: 99%

A Concise review on application of solid lipids and various techniques in the formulation development

Ahire¹,

Kamble²

2023

J. Drug Delivery Ther.

View full text Add to dashboard Cite

show abstract

“…Calotropis procera, a member of the Apocynaceae family, is a softly wooded, perennial shrub with few stems, branches, and leaves that are concentrated near the growing tip and have antimicrobial, anthelmintic, antioxidant, antimalarial, nematocidal, anticancer, antiinflammatory properties 43,44 . A study indicated that Calotropis procera leaf powder and amprolium had comparable activity against coccidiosis in chickens 46 .…”

Section: Calotropis Procera (Madar)mentioning

confidence: 99%

Potential of Anthelmintic Herbal Drugs against Gastrointestinal Nematodes in Farm Animals: A Review

Sadr,

Ahmadi Simab,

Kasaei

et al. 2022

Farm Anim. Health Nutr.

View full text Add to dashboard Cite

Gastrointestinal (GI) nematode infections are one of the most prevalent and significant problems in livestock worldwide. This study aimed to review the potential of anthelmintic herbal drugs against gastrointestinal nematodes in farm animals. Anthelmintic drugs are the most common method of controlling GI nematodes since they are simple, cheap, and provide therapeutic and prophylactic protection. However, the problem has become complicated due to the emergence of resistance to anthelmintic drugs because anthelmintic drugs are used indiscriminately to treat parasitic diseases. Anthelmintic resistance in GI nematodes of ruminants is a global problem. Many domestic animals possess multi-class resistance to all classes of anthelmintics. Synthetic anthelmintics could be unsafe as they can cause side effects and toxicity. Therefore, plants are used to develop and discover novel substances acting as anthelmintics. Herbal drugs have become increasingly popular because of their fewer side effects in recent years. Consequently, the demand for herbal formulations of anthelmintic drugs is increasing. The development of instrumental analysis accelerates the preparation of phytochemical constituents and their standardization, and this field is becoming critical for research.

show abstract

An Overview of Pelletization Techniques Used in Multiparticulate Drug Delivery System

Cited by 2 publications

References 3 publications

A Concise review on application of solid lipids and various techniques in the formulation development

A Concise review on application of solid lipids and various techniques in the formulation development

Potential of Anthelmintic Herbal Drugs against Gastrointestinal Nematodes in Farm Animals: A Review

Contact Info

Product

Resources

About