An overview on traditional uses and pharmacological profile of Acorus calamus Linn. (Sweet flag) and other Acorus species

Rajput, Sandeep B.; Tonge, Madan B.; Karuppayil, Sankunny Mohan

doi:10.1016/j.phymed.2013.09.020

Cited by 164 publications

(105 citation statements)

References 47 publications

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“…The chemical constituents such as β-Asarone (isoasarone), α-Asarone, elemicine, cis-isoelemicine, cis and trans isoeugenol and their methyl ethers, camphene, P-cymene, β-gurjunene, α-selinene, β-cadinene, camphor, terpinen-4-ol, α-terpineol and α-calacorene, acorone, acorenone, acoragermacrone, 2-deca-4,7-dienol,shyobunones, isohyobunones, calamusenone, linalool and pre-isocalamendiol are present. The plant is reported to possess Anti-diabetic, antihypertensive, nootropic, antiepileptic, Neuromodulatory, Antidepressant, Anti-HIV, cytotoxic, Anticancer, Antioxidant, Immunosuppressive, Radioprotection and DNA Repair, Woundhealing, Coronary Vasodilator, Antispasmodic and Antidiarrhoeal, Anti-inflammatory, Insulin Sensitizing, Synergistic Anthelmintic, Antihepatotoxic, Anti-ischemic Heart Disease, Antifungal, Antipyretic, Bronchodilatory, Antibacterial, analgesic, Licicidal, Mosquito Larvicidal and Antispasmodic activity 80 .…”

Section: Vacha (Acorus Calamus L)mentioning

confidence: 99%

A Review on Kumarabharana Prasha: A Novel Ayurvedic Electuary

Mohan¹,

Shailaja²,

Gr³

et al. 2018

Int. J. Res. Ayurveda Pharm.

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The process of licking and gulping it is called as Lehana. The substance subjected for Lehana is called Lehya, this concept is also adopted in drug delivery for neonates and infants where the proposed drug is mixed with any of honey, sugar, ghee, etc made into lickables and fed to child. The purpose and object of Lehana karma look to prevent the diseases by establishing due immunity and to promote the physical and psychic strength providing nutrition. The broad spectrum actions of Kumarabharana Prasha may be attributed to its constituent's namely Bhasmas (calx) of Swarna (Gold), Rajata (Silver), Pravala (coral)and Choorna of Yastimadhu (Glycyrrhiza glabra Linn.), Amalaki (Emblica officinalis Gaertn.), Ashwagandha (Withania somnifera (L.) Dunal), Shunti (Zingiber officinale Roscoe), Pippali (Piper longum Linn.), Harithaki (Terminalia chebula Retz.), Vacha (Acorus calamus Linn.) and all these drugs given one Bhavana with Swarasa (extract juice) of Guduchi (Tinospora cordifolia Willd.), Brahmi (Bacopa monnieri Linn.) and Tulsi (Ocimum tenuiflorum Linn.), with honey and ghee. This can be readily administered to child in requisite dose. This article highlights the ingredients, method of preparation, and probable mechanism of action of Kumarabharana Prasha.

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Section: Vacha (Acorus Calamus L)mentioning

confidence: 99%

A Review on Kumarabharana Prasha: A Novel Ayurvedic Electuary

Mohan¹,

Shailaja²,

Gr³

et al. 2018

Int. J. Res. Ayurveda Pharm.

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show abstract

“…Tumbuhan ini berbentuk mirip rumput, tetapi tinggi, menyukai tanah basah dengan daun dan rimpang yang beraroma kuat (Hasan, 2015;Utari et al, 2016;BPPT, 2017). Pengujian awal pada rimpang jeringau merah menunjukkan potensi penghambatan pertumbuhan bakteri Salmonella typhosa yang dapat menyebabkan penyakit tipus, sementara itu pada jeringau putih digunakan sebagai insektisida alami (Simanjorang, 2008;Hasan et al, 2006;Imam et al, 2014;Rajput et al, 2014;Zhang et al, 2016).…”

Section: Pendahuluanunclassified

Bioactive Component, Antioxidant Activity, and Fatty Acid Profile of Red Beewort (Acorus sp) and White Beewort (Acorus calamus)

Sofyan

Widodo²,

Natsir³

2017

JTP

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ABSTRAKJeringau merah (Acorus sp) dan jeringau putih (Acorus calamus) merupakan tanaman dari famili Araceae yang rimpangnya dijadikan bahan obat-obatan. Antioksidan merupakan senyawa yang dapat menghambat reaksi oksidasi, dengan mengikat radikal bebas dan molekul yang sangat reaktif sehingga kerusakan sel akan dihambat. Penelitian ini bertujuan untuk menganalisis senyawa bioaktif, aktivitas antioksidan dan profil asam lemak pada jeringau merah dan jeringau putih sehingga dapat digunakan sebagai bahan tambahan dalam makanan, pakan serta sebagai sumber antioksidan alami. Bahan yang digunakan dalam penelitian ini adalah rimpang jeringau merah dan jeringau putih. Hasil analisis menunjukan kandungan flavonoid dan aktivitas antioksidan (IC50) pada jeringau merah masing-masing sebesar 33.76 % b/b dan 0.22 mg/ml sedangkan tepung rimpang jeringau putih sebesar 3.84 % b/b dan 0.49 mg/ml. Jenis asam lemak yang dominan menyusun fraksi lipida rimpang jeringau merah dan jeringau putih adalah laurat dan palmitat (unsaturated fatty acid). Asam lemak jenuhnya terdiri dari 7 macam asam lemak dengan asam palmitat sebagai komponen utamanya. Sementara itu, pada rimpang jeringau merah mengandung asam linoleat, sedangkan pada jeringau putih tidak ada. Penelitian ini menunjukkan bahwa rimpang jeringau merah dan jeringau putih dapat digunakan sebagai bahan tambahan dalam makanan, pakan, serta sebagai sumber antioksidan alami Kata kunci : Antioksidan, asam lemak, Flavonoid, Jeringau ABSTRACT Red cypress (Acorus sp) and white jeringau (Acorus calamus) are plants of the Araceae family whose rhizome is made into medicinal materials. Antioxidants are compounds that can inhibit oxidation reactions, by binding to free radicals and highly reactive molecules so that cell damage will be inhibited. This study aims to analyze bioactive compounds, antioxidant activity and fatty acid profiles in red and

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“…Acorus tatarinowii has been used in oriental medicines to ameliorate learning and memory deficits [7–9]. For example, it is used as a component in some Chinese herbal formulas, such as Kai-Xin-San [10, 11] and Chong-Myung-Tang [12, 13], which have been applied to improve memory function.…”

Section: Introductionmentioning

confidence: 99%

“…For example, it is used as a component in some Chinese herbal formulas, such as Kai-Xin-San [10, 11] and Chong-Myung-Tang [12, 13], which have been applied to improve memory function. Acorus tatarinowii contains volatile oils, consisting mainly of α-asarone (8.8–13.7%) and β-asarone (63.2–81.2%) [7, 9]. β-asarone can easily pass through the blood brain barrier (BBB) [14] and substantial experimental evidence indicates that β-asarone is the active ingredient for attenuating learning and memory deficits [15–17].…”

Section: Introductionmentioning

confidence: 99%

β-Asarone Rescues Pb-Induced Impairments of Spatial Memory and Synaptogenesis in Rats

et al. 2016

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Chronic lead (Pb) exposure causes cognitive deficits. This study aimed to explore the neuroprotective effect and mechanism of β-asarone, an active component from Chinese Herbs Acorus tatarinowii Schott, to alleviate impairments of spatial memory and synaptogenesis in Pb-exposed rats. Both Sprague-Dawley developmental rat pups and adult rats were used in the study. Developmental rat pups were exposed to Pb throughout the lactation period and β-asarone (10, 40mg kg-1, respectively) was given intraperitoneally from postnatal day 14 to 21. Also, the adult rats were exposed to Pb from embryo stage to 11 weeks old and β-asarone (2.5, 10, 40mg kg-1, respectively) was given from 9 to 11 weeks old. The level of β-asarone in brain tissue was measured by High Performance Liquid Chromatography. The Morris water maze test and Golgi-Cox staining method were used to assess spatial memory ability and synaptogenesis. The protein expression of NR2B subunit of NMDA receptor, Activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) and Wnt family member 7A (Wnt7a) in hippocampus, as well as mRNA expression of Arc/Arg3.1 and Wnt7a, was also explored. We found that β-asarone could pass through the blood brain barrier quickly. And β-asarone effectively attenuated Pb-induced reduction of spine density in hippocampal CA1 and dentate gyrus areas in a dose-dependent manner both in developmental and adult rats, meanwhile the Pb-induced impairments of learning and memory were partially rescued. In addition, β-asarone effectively up-regulated the protein expression of NR2B, Arc and Wnt7a, as well as the mRNA levels of Arc/Arg3.1 and Wnt7a, which had been suppressed by Pb exposure. The results suggest the neuroprotective properties of β-asarone against Pb-induced memory impairments, and the effect is possibly through the regulation of synaptogenesis, which is mediated via Arc/Arg3.1 and Wnt pathway.

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An overview on traditional uses and pharmacological profile of Acorus calamus Linn. (Sweet flag) and other Acorus species

Cited by 164 publications

References 47 publications

A Review on Kumarabharana Prasha: A Novel Ayurvedic Electuary

A Review on Kumarabharana Prasha: A Novel Ayurvedic Electuary

Bioactive Component, Antioxidant Activity, and Fatty Acid Profile of Red Beewort (Acorus sp) and White Beewort (Acorus calamus)

β-Asarone Rescues Pb-Induced Impairments of Spatial Memory and Synaptogenesis in Rats

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