An overview to electrochemical biosensors and sensors for the detection of environmental contaminants

Khanmohammadi, Akbar; Ghazizadeh, Arash Jalili; Hashemi, Pegah; Afkhami, Abbas; Arduini, Fabiana; Bagheri, Hasan

doi:10.1007/s13738-020-01940-z

Cited by 144 publications

(59 citation statements)

References 161 publications

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“…Several reviews report on electrochemical sensing for water quality analysis [ 8 , 9 ]. Some of them focus on one type or a group of contaminants, such as the advances in nitrate monitoring in the environment and food products [ 10 ], the detection of phosphate -based on cobalt by potentiometric method and the progress of the development of electrochemical sensors for heavy metal ions [ 11 , 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

A Review of Nanocomposite-Modified Electrochemical Sensors for Water Quality Monitoring

Kanoun

Lazarević‐Pašti

Pašti

et al. 2021

Sensors

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Electrochemical sensors play a significant role in detecting chemical ions, molecules, and pathogens in water and other applications. These sensors are sensitive, portable, fast, inexpensive, and suitable for online and in-situ measurements compared to other methods. They can provide the detection for any compound that can undergo certain transformations within a potential window. It enables applications in multiple ion detection, mainly since these sensors are primarily non-specific. In this paper, we provide a survey of electrochemical sensors for the detection of water contaminants, i.e., pesticides, nitrate, nitrite, phosphorus, water hardeners, disinfectant, and other emergent contaminants (phenol, estrogen, gallic acid etc.). We focus on the influence of surface modification of the working electrodes by carbon nanomaterials, metallic nanostructures, imprinted polymers and evaluate the corresponding sensing performance. Especially for pesticides, which are challenging and need special care, we highlight biosensors, such as enzymatic sensors, immunobiosensor, aptasensors, and biomimetic sensors. We discuss the sensors’ overall performance, especially concerning real-sample performance and the capability for actual field application.

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Section: Introductionmentioning

confidence: 99%

A Review of Nanocomposite-Modified Electrochemical Sensors for Water Quality Monitoring

Kanoun

Lazarević‐Pašti

Pašti

et al. 2021

Sensors

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“…A variety of new sensing platforms based on relatively low cost and simple operational routes are alternatives such as electrochemical methods, surface plasmon resonance detections, quartz crystal microbalance, chemiluminescence (CL), fluorescence methods, etc. [5][6][7]. Among them, fluorescence methods have the advantages of high sensitivity, high accuracy, and relative simplicity.…”

Section: Cds As Hms Sensormentioning

confidence: 99%

Recent advances in fluorescence probes based on carbon dots for sensing and speciation of heavy metals

2020

Nanophotonics

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Heavy metal (HM) pollution is a major global concern. Carbon dots (CDs) have demonstrated unique properties as sensing platforms for HMs detection. This review summarizes the progress made in recent years in fluorescence methods to determine HMs and their species using CDs. First, the strategies to synthesize and purify CDs are reviewed. The photoluminescence principles of CDs and their sensing mechanisms as HMs sensors are then summarized. The binding strategies between CDs and HMs are proposed to provide salient principles to design desirable CD-based HMs sensors. The preparation and merits of “turn-on” and ratiometric CDs for HMs detection with higher accuracy are discussed compared with commonly used “turn-off” sensors. Subsequently, the progress on detecting single HM ions, multi-HMs, and different metal species in solution, and the development of gel/solid-state sensor platforms such as paper-based devices, sensor arrays, hydrogels, polymer films, and ion-imprinted polymers are critically accessed. Furthermore, the advances in the cell, bacterial, plant, and animal bioimaging of HMs with CDs as promising bioimaging reagents are presented. Finally, the challenges and prospects of CDs as HMs sensors in future investigations are discussed.

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“…Surface enhanced Raman scattering (SERS) is known as an ultrasensitive molecular spectroscopy technique that has no interference from water, making it a distinct advantage in the identification of bio-samples ( Wang et al, 2017 ; Wang et al, 2013 ; Granger et al, 2016 ; Porter et al, 2008 ; Laing et al, 2016 ). Compared with lateral flow immunoassay, photothermal method and electrical biosensor ( Khanmohammadi et al, 2020 ; Karimian et al, 2020 ), SERS-based immunoassay technique does not require sample pretreatment, has high sensitivity for detecting trace amounts of bioparticles, and even be capable of single-molecule detection in special cases, providing an efficient method for the SARS-CoV-2 virus detection ( Jadhav et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Ultrasensitive detection of SARS-CoV-2 spike protein in untreated saliva using SERS-based biosensor

Zhang

Pan

et al. 2021

Biosensors and Bioelectronics

144

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Early diagnosis and monitoring of SARS-CoV-2 virus is essential to control COVID-19 outbreak. In this study, we propose a promising surface enhanced Raman scattering (SERS)-based COVID-19 biosensor for ultrasensitive detection of SARS-CoV-2 virus in untreated saliva. The SERS-immune substrate was fabricated by a novel oil/water/oil (O/W/O) three-phase liquid-liquid interfaces self-assembly method, forming two layers of dense and uniform gold nanoparticle films to ensure the reproducibility and sensitivity of SERS immunoassay. The detection was performed by an immunoreaction between the SARS-CoV-2 spike antibody modified SERS-immune substrate, spike antigen protein and Raman reporter-labeled immuno-Ag nanoparticles. This SERS-based biosensor was able to detect the SARS-CoV-2 spike protein at concentrations of 0.77 fg mL -1 in phosphate-buffered saline and 6.07 fg mL -1 in untreated saliva. The designed SERS-based biosensor exhibited excellent specificity and sensitivity for SARS-CoV-2 virus without any sample pretreatment, providing a potential choice for the early diagnosis of COVID-19.

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An overview to electrochemical biosensors and sensors for the detection of environmental contaminants

Cited by 144 publications

References 161 publications

A Review of Nanocomposite-Modified Electrochemical Sensors for Water Quality Monitoring

A Review of Nanocomposite-Modified Electrochemical Sensors for Water Quality Monitoring

Recent advances in fluorescence probes based on carbon dots for sensing and speciation of heavy metals

Ultrasensitive detection of SARS-CoV-2 spike protein in untreated saliva using SERS-based biosensor

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