An oxidative stress score as a combined measure of the pro-oxidant and anti-oxidant counterparts in patients with coronary artery disease

Vassalle, Cristina; Pratali, Lorenza; Boni, Claudio De; Mercuri, Antonella; Ndreu, Rudina

doi:10.1016/j.clinbiochem.2008.07.005

Cited by 103 publications

(78 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…IMA may show a sensitive biochemical marker, especially for the diagnosis of myocardial ischemia (Sinha et al, 2004). Several reports proved that ischemia induces a cascade of proinflammatory reactions that lead to the production of ROS (Kotur-Stevuljevic et al, 2007;Vassalle et al, 2008). IMA is indicated a marker of ischemia and oxidative stress originating as a consequence of tissue hypoxia (Can et al, 2006;Senes et al, 2007;Lippi et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Ischemia Modified Albumin Levels and Oxidative Stress in Patients with Bladder Cancer

Elli̇dağ¹,

Eren²,

Aydın³

et al. 2013

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Background: Impaired oxidative/antioxidative status plays an important role in the pathogenesis of many diseases like cancer. The aim of this study was to evaluate the levels of the novel marker ischemia modified albumin (IMA) and albumin adjusted-IMA (Adj-IMA) in patients with bladder cancer (BC) as well as its association with total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI). Materials and Methods: Forty male patients with BC (mean age, 67.4±12 years) and forty age-sex matched healthy persons (mean age 56.0±1.7 years) were included in this study. Serum levels of IMA, TAS, TOS were analyzed and Adj-IMA and OSI was calculated. Results: Serum IMA, TOS and OSI values were significantly higher in patients with BC compared to controls (p<0.0001, p=0.01 and p=0.01, respectively), whereas TAS was significantly lower in BC patients (p=0.04). There was no significant difference for serum albumin-adjusted IMA levels between groups (p=0.4). Conclusions: In this study, it was found that there was an impaired oxidative/antioxidant status in favor of oxidative stress in BC patients. This observation was not confirmed by Adj-IMA calculation. There is no published report about serum concentrations of IMA in patients with BC. Further studies are needed to establish the relationship of IMA and oxidative stress parameters in BC and the significance of IMA to other cancers.

show abstract

Section: Introductionmentioning

confidence: 99%

Ischemia Modified Albumin Levels and Oxidative Stress in Patients with Bladder Cancer

Elli̇dağ¹,

Eren²,

Aydın³

et al. 2013

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

show abstract

“…Compounds 25-48 inhibit superoxide ions by 7,4,8,13,3,11,5,14,5,5,6,5,6,6,13,7,7,8,11,8,4,10,7, and 7%, respectively. They inhibit hydroxyl radicals by 13,8,10,18,9,7,11,8,8,11,6,7,9,9,10,11,5,12,8,7,11,10,10, and 8%, respectively, whereas inhibition of microsomal lipid peroxidation is 6,1,8,17,6,7,5,…”

Section: Biologymentioning

confidence: 99%

“…Oxidative stress is intricately involved in the pathogenesis and development of several diseases and more particularly atherosclerosis 1 . It is one of the important factors for the development and progression of CHD (coronary heart disease 2 ).…”

Section: Introductionmentioning

confidence: 99%

Synthesis of 5-aryl-6-cinnamoyl-7-methyl-flavanones as novel antioxidants and antihyperlipidemics

Sharma

Anand

Sharma

et al. 2011

Journal of Enzyme Inhibition and Medicinal Chemistry

View full text Add to dashboard Cite

“…The systemic anti-oxidant condition was indirectly evaluated by measuring total anti-oxidant capacity in plasma using the OXY-adsorbent Test (OXY Diacron, Grosseto, Italy) in a plasma sample (Cesarone et al, 1999;Vassalle et al, 2008). This test is based on the capacity of hypochlorous acid (HClO) to oxidize the physiological antioxidants.…”

Section: Total Anti-oxidant Capacity In Plasmamentioning

confidence: 99%

Suppressed anti-oxidant capacity due to a cellulose-free diet declines further by cigarette smoke in mice

et al. 2012

View full text Add to dashboard Cite

-Dietary fiber, maintaining the gut environment, contributes to better lung function among smokers. This study was aimed to investigate the role of dietary fiber on the anti-oxidant capacity and gut environment during exposure to cigarette smoke. The anti-oxidant capacity as well as caecal levels of organic acids and population of micro-flora in the gut was measured after 4 months' exposure to cigarette smoke in mice (C57BL/6NcrSlc) fed with a cellulose-free diet. Animals were divided into control diet (AIN-93G)/non-smoke, cellulose-free diet/non-smoke, control diet/smoke, and cellulose-free diet/smoke groups. The anti-oxidant capacity in plasma was significantly suppressed by the cellulose-free diet in the non-smoke exposed mice. The suppression in the anti-oxidant capacity further declined following exposure to cigarette smoke. Both these changes in the anti-oxidant capacity were accompanied with changes in some organic acids levels in caecal contents. The anti-oxidant activity was significantly inversely correlated to succinic acid / acetic acid levels balance in caecal contents. In conclusion the cellulose-free diet suppressed the anti-oxidant capacity in mice, and the suppression further decreased by exposure to cigarette smoke. These changes in the anti-oxidant capacity may be related with changes in the gut environment.

show abstract

An oxidative stress score as a combined measure of the pro-oxidant and anti-oxidant counterparts in patients with coronary artery disease

Cited by 103 publications

References 24 publications

Ischemia Modified Albumin Levels and Oxidative Stress in Patients with Bladder Cancer

Ischemia Modified Albumin Levels and Oxidative Stress in Patients with Bladder Cancer

Synthesis of 5-aryl-6-cinnamoyl-7-methyl-flavanones as novel antioxidants and antihyperlipidemics

Suppressed anti-oxidant capacity due to a cellulose-free diet declines further by cigarette smoke in mice

Contact Info

Product

Resources

About