An ultrasensitive fluorescent aptasensor based on truncated aptamer and AGET ATRP for the detection of bisphenol A

Review—Aptasensors: Cutting-Edge Technologies for Bisphenol A Detection as an Endocrine Disruptor

“…This analyzer gave a linearity graph covering concentrations of BPA from 0.0005 to 1.0 ng ml −1 (ppb) with LOD of more than 1 ng ml −1 or ppb. 93 Furthermore, a new aptasensor was fabricated by Guo et al, 94 involving the usage of activators produced by transfer of electrons for atom transfer radical polymerization (AGET ATRP), and truncated aptamer for selective detection of BPA. In this, the hairpin DNAs (hairpins), with the help of heterobifunctional cross-linkers, were made to conjugate with the magnetic beads (MBs).…”

Fluorescent Aptasensors: Design Strategies and Applications in Analyzing Chemical Contamination of Food

“…Bisphenol A (BPA) is mainly used for the production of polycarbonate plastics and epoxy resins, which are widely applied in the manufacturing of food contact materials, such as water pipes, plastic (milk) bottles, and food and drink (milk powder) packaging/cans . It has been reported that BPA can interfere with the basic physiological processes and cause various disorders, including metabolic disease, thyroid dysfunction, neurological defects, and cancer. , In many countries, the use of BPA in plastic infant feeding bottles is prohibited . As a promising tool to monitor BPA, aptasensors have been developed for BPA detection with significant progress …”

“…202 It has been reported that BPA can interfere with the basic physiological processes and cause various disorders, including metabolic disease, thyroid dysfunction, neurological defects, and cancer. 203,204 In many countries, the use of BPA in plastic infant feeding bottles is prohibited. 205 As a promising tool to monitor BPA, aptasensors have been developed for BPA detection with significant progress.…”