An unusual case of Corynebacterium striatum endocarditis in a patient with congenital lymphedema and rheumatic heart disease

Abstract

Corynebacterium striatum (C. striatum) is a ubiquitous saprophyte with a potential to cause bacteremia. We report the first case of C. striatum endocarditis in a patient with congenital lymphedema and rheumatic heart disease.

Treat Me Well or Will Resist: Uptake of Mobile Genetic Elements Determine the Resistome of Corynebacterium striatum

“…However, different studies have increasingly recognized C. striatum as the etiologic agent of various infections with signs and symptoms ranging from mild to severe to fatal outcomes, including bacteremia, endocarditis, meningitis, osteomyelitis, arthritis, corneal infection, and sinusitis [ 8 , 9 ]. Moreover, cases of infection of the respiratory tract, surgical wounds, skin lesions, or the eye, genital and urinary tract due to C. striatum strains have been also reported [ 10 , 11 , 12 ]. Previous studies verified nosocomial spread of MDR C. striatum strains, especially in patients of intensive care units and surgical wards making use of medical devices or with prolonged exposure to broad-spectrum antimicrobials [ 13 , 14 , 15 ].…”

Three-valve Endocarditis Caused by Corynebacterium striatum

“…C. striatum is an aerobic, Gram-positive bacillus that has been emerging as a nosocomial opportunistic pathogen 1) 2) and can rarely be associated with native valve endocarditis. 3) In this case with poor medical compliance, a dialysis catheter was thought to result in C. striatum endocarditis with severe, disastrous destruction of the three cardiac valves requiring valvular replacement. 3D TEE can be helpful for meticulous evaluation of valvular morphology and function in patients with C. striatum endocarditis.…”

Simultaneous triple valve replacement for triple valve infective endocarditis with intact cardiac skeleton

“…5 C. striatum cultured in our case is only 0.2% to 0.4% of cases of native valve endocarditis. 6 Valvular insufficiency, embolic events, and abscess formation are the most common complications of right-sided infective endocarditis. 7 In our case, despite the very large size of the vegetation and extensive tricuspid valve leaflet destruction, massive destruction of the mitral and aortic valves, and relative delay to surgical treatment, we found no evidence of perivalvular or aortomitral curtain abscess formation or destruction on perioperative echocardiography or from surgical observation.…”