An update to the pathogenesis for monoclonal gammopathy of renal significance

Zuo, Chao; Zhu, Yuanchang; Xu, Gaosi

doi:10.1007/s00277-020-03971-1

Cited by 4 publications

(1 citation statement)

References 101 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various hematologic malignancies secrete monoclonal immunoglobulins and light chains (LCs), which are an important cause of kidney disease. 4 , 18 , 54 , 55 , 56 , 57 , 58 Clonal plasma cells or B-cell disorders that produce these paraproteins are collectively known as dysproteinemias, which include multiple myeloma, lymphoproliferative disorders, and monoclonal gammopathy of renal significance. These secreted paraproteins may form crystals and cause crystal-related kidney injury that may involve various parts of the nephron including the preglomerular capillaries, glomeruli, and tubular system, ranging from the proximal tubules to the cortical collecting ducts.…”

Section: Pathogenesis Of Crystalline Nephropathiesmentioning

confidence: 99%

The Crystalline Nephropathies

Perazella

Herlitz

2021

Kidney International Reports

View full text Add to dashboard Cite

This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

show abstract