An Updated Liquid Chromatographic Assay for the Determination of Glyphosate in Technical Material and Formulations

Gavlick, Walter K.; Tomkins, David F

doi:10.1093/jaoac/91.1.1

Cited by 6 publications

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“…50‐fold. Yet, such reports are minority and chromatographic and electrophoretic methods incorporating UV–vis absorption, fluorescence, mass spectrometry, and electrochemical detection prevail . Also, the use of modified electrode for direct voltammetric determination of glyphosate has been described in literature .…”

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Determination of glyphosate and AMPA on polyester‐toner electrophoresis microchip with contactless conductivity detection

et al. 2013

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This paper reports a method for rapid, simple, direct, and reproducible determination of glyphosate and its major metabolite aminomethylphosphonic acid (AMPA). The platform described herein uses polyester-toner microchips incorporating capacitively coupled contactless conductivity detection and electrophoresis separation of the analytes. The polyester-toner microchip presented 150 μm-wide and 12 μm-deep microchannels, with injection and separation lengths of 10 and 40 mm long, respectively. The best results were obtained with 320 kHz frequency, 4.5 Vpp excitation voltage, 80 mmol/L CHES/Tris buffer at pH 8.8, injection in -1.0 kV for 7 s, and separation in -1.5 kV. RSD values related to the peak areas for glyphosate and AMPA were 1.5 and 3.3% and 10.1 and 8.6% for intra- and interchip assays, respectively. The detection limits were 45.1 and 70.5 μmol/L, respectively, without any attempt of preconcentration of the analytes. Finally, the method was applied to river water samples in which glyphosate and AMPA (1.0 mmol/L each) were added. The recovery results were 87.4 and 83.7% for glyphosate and AMPA, respectively. The recovery percentages and LOD values obtained here were similar to others reported in the literature.

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confidence: 99%

Determination of glyphosate and AMPA on polyester‐toner electrophoresis microchip with contactless conductivity detection

et al. 2013

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“…The exercise consisted of four runs in which the laboratories were free in choosing analytical methods to determine trace elements in freeze-dried animal serum. Laboratory performances were evaluated by the study of statistical functions as coefficients of variation (CV), Youden plot and z-score value [62] Collaborative studies for cereal analysis [10] Practical digest for evaluating the uncertainty of analytical assays from validation data according to the LGC/VAM protocol [63] Statistical methods for use in proficiency testing by interlaboratory studies, International Organization for Standardization [13] Youden analysis of Karl Fisher titration data from an interlaboratory study determining water in animal feed, grain and forage [64] Establishing measurement traceability in clinical chemistry: cholesterol, progesterone and aldosterone in serum [65] Worldwide and regional intercomparison for the determination of organochlorine compounds and petroleum hydrocarbons in mussel tissue IAEA-432 [66] Interlaboratory study on the determination of ascorbic acid in serum [67] An intercomparison of in vitro chlorophyll-a determination [68] Guide about collaborative studies to validate characteristics of an analytical method [69] Youden method application to result in total and dissolved organic carbon in surface waters [70] Interlaboratory exercise conducted within the framework of a hydrological project on underground water [71] Interlaboratory study on the determination of trace elements in sea water [72] State of the art with respect to the selection and use of proficiency testing schemes and the interpretation of results and evaluations given in proficiency testing schemes [15] Interlaboratory studies in analytical chemistry: method performance studies (collaborative trials), laboratory-performance studies (proficiency tests), collaborative bias evaluation, interlaboratory evaluation of to-be standard methods as well as certification studies for reference materials [12] Youden Two-Sample Method http://dx.doi.org/10.5772/66411…”

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Youden Two-Sample Method

Martin¹,

Velázquez²,

Asuero³

2017

Quality Control and Assurance - An Ancient Greek Term Re-Mastered

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The results obtained when testing materials, equipment and procedures are not generally identical. Factors that influence the magnitude of the results are not fully controllable. As such, the interpretation and analysis of results must take into account the variations caused by numerous and random unavoidable causes. Intercomparison exercises are considered of being of importance, as they do allow the examination of the analytical process and their generated results. Youden plot is particularly aimed at interlaboratory comparisons. The raw results provided by the participating laboratories are treated by a statistical method applied by the centre performing the trial. In order to materialize this, two similar materials with small differences in the concentration of the characteristics are required. The advantage of Youden analysis is its ability to separate the random errors with a minimum effort by participants in the design from the point of view of the analytical requirement. This book chapter illustrates the method that has been applied to elaborate on data covering a diverse scientific field: polyunsaturated fatty acids in fat and oils, total blood cholesterol and aspirin in pharmaceutical preparations. Finally, liquid chromatography with tandem mass spectrometry detector has been applied to the determination of an emerging contaminant, methylparaben (MeP), in surface waters.

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“…Há poucas pesquisas que abordam este tipo de análise para controle de qualidade dos produtos técnicos e/ou formulados de glifosato. [93][94][95][96] No entanto, para isso, existem métodos oficiais, tais como os da AOAC (Association of Analiytical Communities) e da CIPAC (Collaborative International Pesticides Analytical Council), porém estes são bastante trabalhosos, além de desatualizados. 97,98 Apesar desses métodos não abordarem análises de RMN, o emprego dessa técnica é recomendado aqui no Brasil para análises de cinco bateladas (Five Batch Analysis) e aparece descrita na instrução normativa brasileira, a qual teve sua última consulta pública realizada em janeiro de 2011.…”

Section: Medidas Quantitativas De Rmn No Domínio Do Tempo (Rmn-dt)unclassified

Desenvolvimento de métodos de RMN para controle de qualidade de produtos farmacêuticos e agrícolas

Santos¹

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, quem eu admiro muito, pela orientação, pelos conhecimentos transmitidos e pela amizade que contribuíram muito para o meu crescimento profissional e pessoal. Ao Professor Doutor Guido F. Pauli, que me recebeu em seu grupo de pesquisa para a realização dos estudos envolvendo RMN e a planta Cardo-leiteiro, me dando a oportunidade de adquirir novas experiências acadêmicas e de vida. Ao Professor Daniel R. Cardoso por ter disponibilizado o uso da balança de seu laboratório, viabilizando a validação do método para quantificação de glifosato. Aos funcionários da Embrapa Instrumentação pela ajuda nos momentos necessários, principalmente aos técnicos do laboratório de RMN, Viviane e Marcelo. Especialmente ele, pela construção dos padrões externos. A todos os alunos do grupo de RMN da Embrapa Instrumentação desses 5 anos de trabalho... em especial, à Roberta, à Dani e ao Tiago pela amizade e contribuição nos ensaios de precisão intermediária. Agradeço também ao Tiago pela parceria no estudo do FDM e à Dani pela parceria nas análises de azeites. Aos alunos do grupo do Professor Pauli que conviveram comigo durante os seis meses que estive por lá, me ajudando sempre com muita paciência e compreensão. Principalmente ao José pelos ensinamentos e a Joo-Won pela amizade. Aos meus familiares... em especial, minha irmã, Francine, minha mãe, Luzia, e meu pai, Francisco, por mais uma vez acreditarem em mim e me darem o suporte necessário nos momentos difíceis. Ao Renato pela compreensão, apoio e palavras de incentivo, sempre com muito amor e carinho. E aos pais dele, Antonio Carlos Vigatto e Elisabeth da Silva Vigatto, por toda colaboração, possibilitando a conclusão deste trabalho. A todos os amigos pelas discussões científicas, bate-papos e momentos de descontração. A FAPESP e a CAPES pelos apoios financeiros.

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An Updated Liquid Chromatographic Assay for the Determination of Glyphosate in Technical Material and Formulations

Cited by 6 publications

References 0 publications

Determination of glyphosate and AMPA on polyester‐toner electrophoresis microchip with contactless conductivity detection

Determination of glyphosate and AMPA on polyester‐toner electrophoresis microchip with contactless conductivity detection

Youden Two-Sample Method

Desenvolvimento de métodos de RMN para controle de qualidade de produtos farmacêuticos e agrícolas

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