An upper lip tumour as the presenting symptom of metastatic renal cancer

Syryło, Tomasz; Syryło, Agnieszka; Jurkiewicz, Dariusz; Zieliński, Henryk; Piętka, Tomasz

doi:10.1016/s0030-6657(10)70614-4

Cited by 6 publications

(3 citation statements)

References 5 publications

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“…Some of these metastatic sites in head and neck that have been reported in the literature include parotid [13, 14], paranasal sinuses [15], nasopharynx [15], oral cavity [16], and lip [17]. Within the literature, investigators determined an interval of 5 to 36 months between the appearance of the primary tumor and the metastasis.…”

Section: Discussionmentioning

confidence: 99%

Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation

Jallu

Latoo

Pampori

2013

Case Reports in Urology

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Introduction. Renal cell carcinoma accounts for approximately 3% of adult malignancies and 90–95% of neoplasms arising from the kidney. This disease is characterized by a lack of early warning signs, diverse clinical manifestations, and resistance to radiation and chemotherapy. Approximately one-third of patients with renal cell carcinoma have metastatic disease at initial presentation. Fifteen percent of patients with renal cell carcinoma are said to present with metastases in the head and neck region. Most of the metastases from RCC to the head and neck involve the thyroid gland. The head and neck are unusual sites for metastases, but skin, skeletal muscle, thyroid gland, nasal cavity and paranasal sinus metastases have been reported. Case Report. The following report describes a rare case where the patient presented with mandibular swelling of short duration as the primary complaint without any symptom or sign pertaining to urinary tract and was found to have renal cell carcinoma on further workup. Conclusion. Metastatic renal cell carcinoma is a diagnostic dilemma especially when there is no pointer historically towards renal cell carcinoma as was in our case. An unusual vascular osteolytic lesion in head and neck in a middle-aged person should be dealt with high index of suspicion with renal cell carcinoma at the back of the mind.

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Section: Discussionmentioning

confidence: 99%

Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation

Jallu

Latoo

Pampori

2013

Case Reports in Urology

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“…The full listing of cases can be found in Table 1 . [ 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 ]…”

Section: Discussionmentioning

confidence: 99%

Renal cell carcinoma metastatic to the maxillary gingiva: A case report and review of the literature

Vasilyeva

Peters

Philipone

et al. 2018

J Oral Maxillofac Pathol

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Tumor metastasis to the oral cavity is rare and is usually an indication of late-stage disease and poor prognosis. While, there are reports of renal cell carcinoma (RCC) metastatic to oral cavity, vast majority of them are to the jaw. Herein, we present a case of a 78-year-old woman with RCC metastasis limited to the oral soft tissue without any bone involvement. As the lesion solely involved maxillary gingiva, it clinically mimicked that of a pyogenic granuloma, which is a reactive, nonneoplastic condition. This case was further complicated as the patient was unaware of primary cancer and appeared to be in good physical health. Her oral metastasis marked the initial manifestation of an otherwise silent primary renal cancer.

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“…This highlights the importance of full body imaging to identify whether the patient has previously undergone surgery for head and neck neoplasms, to avoid inaccurately diagnosing a newly formed metastasis as the recurrence of a former tumor. A third of the previously identified cases of patients with head and neck RCC metastases have been reported on the facial skin area ( 4 – 11 ), although the parotid gland, paranasal sinuses and tongue are also common locations. In addition, single cases of nephroblastoma (also termed, Wilms’ tumor) and renal sarcomas have been reported in the head and neck area ( 12 , 13 ).…”

Section: Discussionmentioning

confidence: 99%

Rapidly growing and ulcerating metastatic renal cell carcinoma of the lower lip: A case report and review of the literature

et al. 2014

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Renal cell carcinomas (RCCs) have a tendency to metastasize at an early stage, therefore, the patients frequently exhibit metastatic disease at the time of diagnosis. Common locations for the metastases are adjacent organs and abdominal lymph nodes; however, occasionally metastasis to the peripheral organs may be the initial clinical symptom. The 71-year-old male patient in the current case suffered from radioresistant and aggressively behaving RCC metastasis in the mandible and lower lip, which was successfully managed by surgical resection. RCC metastasis to the facial area is considered to be uncommon based on a review of the existing literature. RCC are somewhat radioresistant and therefore, palliative surgery must be considered when treating patients with this metastatic disease.

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An upper lip tumour as the presenting symptom of metastatic renal cancer

Cited by 6 publications

References 5 publications

Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation

Rare Case of Renal Cell Carcinoma with Mandibular Swelling as Primary Presentation

Renal cell carcinoma metastatic to the maxillary gingiva: A case report and review of the literature

Rapidly growing and ulcerating metastatic renal cell carcinoma of the lower lip: A case report and review of the literature

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