Anaesthesia in craniosynostosis

Anaesthetic management of craniosynostosis repair – A retrospective study

“…As compared to the Cárdenas study,[ 3 ] our study had a higher number of children with predicted difficult airway (58.3 vs. 76%) and difficult intubation (5.2 vs. 15%) needing fiberoptic bronchoscopy (FOB) or video laryngoscope. In terms of blood loss, our study results were similar to other studies that showed that SC had more blood loss as compared to non-syndromic children.…”

“…Different dose regimens of TXA have been used to reduce the blood loss in various surgeries ranging from 10–100 mg/kg, followed by 1–10 mg/kg/hr infusion. [ 3 ] In our institution, we used 20 mg/kg bolus followed by 1 mg/kg/hr infusion or 5 mg/kg bolus after 3 hours of administration of the first dose, which was similar to the study by Dadure et al . [ 7 ]…”

“…[ 9 ] In our study population, 64% received noradrenaline for the haemodynamic support, which was higher than the other study results. [ 3 ] This may be due to the routine practice of starting a low dose of noradrenaline (0.02 μg/kg/min) to combat the anaesthesia-induced vasodilation and to keep the haemodynamics within 20% of baseline. One child received adrenaline along with noradrenaline because of a severe allergic non-haemolytic blood transfusion reaction.…”