Abstract:The patterns of synaptic connections between neurons in the brain are key determinants of behaviour, but how specific neural circuits lead to distinct behaviours is largely unknown. Cell recognition molecules that mediate interactions between neurons play a crucial role in establishing synaptic connections. Down Syndrome Cell Adhesion Molecule 2 (Dscam2) is required for establishing modularity in the visual system. Dscam2 null flies have a disorganized visual system, lack boundaries between neighbouring module… Show more
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