Analysis of bioactive phytochemical compound of (Cyperus aucheri Jaub.) by using gas chromatography –mass spectrometry

Abu-Serag, Nidaa Adnan; Al-Garaawi, N. I.; Ali, A. M.; Alsirrag, M. A.

doi:10.1088/1755-1315/388/1/012063

Cited by 5 publications

(4 citation statements)

References 5 publications

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“…Additional quantitative data were obtained by gas chromatography coupled to mass spectrometry (GC/MS). The experimental design was adapted from that used by Li and Fingas, while the analysis of the mass spectrum followed that reported for C14 by Abu-Serag et al and confirmed a molecular ion for C14 at 239.4 AMU …”

Section: Resultsmentioning

confidence: 99%

“…The experimental design was adapted from that used by Li and Fingas, 82 while the analysis of the mass spectrum followed that reported for C14 by Abu-Serag et al and confirmed a molecular ion for C14 at 239.4 AMU. 83 GC on control samples showed that C14 detection at low concentrations was at the instrumental limit of ∼1−5 mg/L or 1−5 ppm (Figure 9(Left)). The GC data for the octane extract after WG-1 immersion in PB for 1, 2, and 7 days at 37 °C are shown in Figure 9(Right).…”

Section: Antimicrobial Tests Minimum Inhibitory Concentration (Mic) A...mentioning

confidence: 99%

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Facile Modification of Medical-Grade Silicone for Antimicrobial Effectiveness and Biocompatibility: A Potential Therapeutic Strategy against Bacterial Biofilms

Wynne,

Zolotarskaya,

Jarrell

et al. 2023

ACS Appl. Mater. Interfaces

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A one-step modification of biomedical silicone tubing with N,N-dimethyltetradecylamine, C14, results in a composition designated WinGard-1 (WG-1, 1.1 wt % C14). A surface-active silicon-amine phase (SAP) is proposed to account for increased wettability and increased surface charge. To understand the mechanism of antimicrobial effectiveness, several procedures were employed to detect whether C14 leaching occurred. An immersion-growth (IG) test was developed that required knowing the bacterial Minimum Inhibitory Concentrations (MICs) and Minimum Biocidal Concentrations (MBCs). The C14 MIC and MBC for Gm– uropathogenic E. coli (UPEC), commonly associated with catheter-associated urinary tract infections (CAUTI), were 10 and 20 μg/mL, respectively. After prior immersion of WG-1 silicone segments in a growth medium from 1 to 28 d, the IG test for the medium showed normal growth for UPEC over 24 h, indicating that the concentration of C14 must be less than the MIC, 10 μg/mL. GC-MS and studies of the medium inside and outside a dialysis bag containing WG-1 silicone segments supported de minimis leaching. Consequently, a 5 log UPEC reduction (99.999% kill) in 24 h using the shake flask test (ASTM E2149) cannot be due to leaching and is ascribed to contact kill. Interestingly, although the MBC was greater than 100 μg/mL for Pseudomonas aeruginosa, WG-1 silicone affected an 80% reduction via a 24 h shake flask test. For other bacteria and Candida albicans , greater than 99.9% shake flask kill may be understood by proposing increased wettability and concentration of charge illustrated in the TOC. De minimis leaching places WG-1 silicone at an advantage over conventional anti-infectives that rely on leaching of an antibiotic or heavy metals such as silver. The facile process for preparation of WG-1 silicone combined with biocidal effectiveness comprises progress toward the goals of device designation from the FDA for WG-1 and clearance.

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Section: Resultsmentioning

confidence: 99%

Section: Antimicrobial Tests Minimum Inhibitory Concentration (Mic) A...mentioning

confidence: 99%

Facile Modification of Medical-Grade Silicone for Antimicrobial Effectiveness and Biocompatibility: A Potential Therapeutic Strategy against Bacterial Biofilms

Wynne,

Zolotarskaya,

Jarrell

et al. 2023

ACS Appl. Mater. Interfaces

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“…It is an essential oil found in medicinal plants Premna tomentosa (Priyadarshini et al 2017), in the leaves and fruits of Piper aduncum (Wibawa et al 2019), Artemesia lavandulaefolia (Yuan et al 2010), Cunninghamia lanceolata biomass (Qing-Zhia et al 2012), a bioactive phytochemical compound of Cyperus aucheri Jaub. (Abu-Serag et al 2019), and in Chinese ginger (Zingiber officinale Roscoe) rhizomes (Ding et al 2012;Choudhari and Kareppa 2013).…”

Section: Discussionmentioning

confidence: 99%

Phytochemical and gas chromatography-mass spectrometry profiling of two plant parts of Sandoricum koetjape

SAADAH¹,

TULANDI²,

ROHMAN³

2022

Biodiversitas

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Abstract. Saadah S, Tulandi SM, Rohman RA. 2022. Phytochemical and gas chromatography-mass spectrometry profiling of two plant parts of Sandoricum koetjape. Biodiversitas 23: 6199-6207. Sandoricum koetjape has been used in traditional Indonesian medicine for centuries. In Indonesia, the stem and leaves were used to treat helminthiasis, cough, stomachache, diarrhea, bloating, leucorrhoea, colic, and fever. To ascertain the phytochemical constituents of each plant part, and provide a sufficient basis for clinical application, so Gas Chromatography-Mass Spectrometry (GC/MS) analysis of stems and leaves was established. Phytochemical screening showed that stems and leaves contained alkaloids, flavonoids, quinone, triterpenoids, and tannin. Total phenolics in the leaves are higher than in the stem. Saponin and steroids were not detected. The GC/MS analysis indicated that the leaf extract contained more identified compounds (30) than the stem extract (28). Both S. koetjape samples contained 1H-Cycloprop[e]azulen-7-ol. The major compounds of the stem extract of S. koetjape are Fonenol (12.89%), 1H-Cyclopenta[1,3]cyclopropa[1,2]benzene (12.54%), and 1H-Cycloprop[e]azulen-7-ol (11.70%), while the major compounds in leaf methanol extract were 14,15-didehydro-Cyclodecacyclotetradecene (23.71%), 1H-Cycloprop[e]azulen-7-ol (17.04%), and Solanesol (8.34%). The two main components of the variable can account for 50.92% of the total variance, according to Principal Component Analysis (PCA) (PC1 is 21.19% and PC2 is 29.74%). These results indicate that the two components effectively categorize samples with distinct characteristics. The groups were divided based on the type of sample used, namely stem and leaf samples. According to the loading plot, 1H Cyclopenta[1,3]cyclopropa[1,2]benzene and Fonenol are two components that are very effective in categorizing samples based on their type. Both metabolites are higher in the stem than in the leaf. However, the metabolites activities of S. koetjape stem and leaves extracts could be revealed by further studies using in silico and in vitro approaches.

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“…About 1μL of them ethanol extract was injected into the GC-MS column using a micro syringe and the scanning was done for 45minutes". [ 18,19]…”

Section: -Constituents Identification Of Extract By Gas Chromatograph...mentioning

confidence: 99%

phytochemical and the antifungal activity of Melia azedarach Ethanol extracts from leaves of Plants in Iraq

Jawad

Garaawi

2022

ijhs

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In the present study a various phytochemical compounds that have been isolated from Melia azedarach and showed phytoconstituents from leaves against three of pathogenic fungi are as follows: Alternaria alternate, Neoscytalidium dimidiatum and Sordaria fimicola. ''The Phytochemical of M. azedarach leaves were exposed to (GC-MS) analysis. The results showed highest activity against reviewed fungal, (Alternaria alternate, Neoscytalidium dimidiatum and Sordaria fimicola). All three concentrations of extract (20,30,40 mg/ml) in respectively" were given a results ( 0.00 )mm in the diameter of colonies. The GC-MS analysis of Melia azedarach leaves parts showed the presence of؛ Ethyl methyl phthalate ؛ diethyl benzene-1,2-dicarboxylate ؛ Methyl hexadecanoate Palmitic acid (hexadecanoic acid) ؛ 11-octadecenoic acid methyl ester ؛2-Hexadecen-1-ol,3,7,11,15-tetramethyl-,(2E,7R,11R)- ؛-9-(Z)-Octadecenoic acid ؛1,16-Hexadecanedicarboxylic acid ؛9(Z),12(E)-Octadecadienoic acid ؛9,19-cyclolanost-24-en-3-ol ؛3-beta-5-alpha-6-beta-trihydroxycholestan ؛4-Stigmasten-3-one ؛9,19-Cyclo-9.beta.-lanost-25-en-3.beta.-ol, 24-methyl-, (24S)- ؛(R,R,R)-alpha-Tocopherol ؛4-(4-ethylcyclohexyl)-1-pentyl-cyclohexene ) ؛4,4-Dimethyl-5-.alpha.-cholestan-3-.beta.-ol ؛ 5alpha-Stigmastan-3,6-dione ؛(22E)-Stigmast-22-en-3-one ؛Cholest-8-en-3.beta.-ol ؛(2-Dodecen-1-yl)succinic anhydride, technical.

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Analysis of bioactive phytochemical compound of (Cyperus aucheri Jaub.) by using gas chromatography –mass spectrometry

Cited by 5 publications

References 5 publications

Facile Modification of Medical-Grade Silicone for Antimicrobial Effectiveness and Biocompatibility: A Potential Therapeutic Strategy against Bacterial Biofilms

Facile Modification of Medical-Grade Silicone for Antimicrobial Effectiveness and Biocompatibility: A Potential Therapeutic Strategy against Bacterial Biofilms

Phytochemical and gas chromatography-mass spectrometry profiling of two plant parts of Sandoricum koetjape

phytochemical and the antifungal activity of Melia azedarach Ethanol extracts from leaves of Plants in Iraq

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