2021
DOI: 10.3126/jpn.v11i2.37681
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Analysis of frozen section compared to permanent section: a 2 year study in a single teritiary care hospital

Abstract: Background: Frozen section is a commonly used tool for intraoperative consultation giving valuable information for patient management. Analysis of diagnosis during frozen section and subsequent permanent section allows the pathologist to review the diagnostic accuracy. Materials and methods: In this 2-year retrospective study, 66 tissues received for intraoperative consultation were studied with the corresponding permanent sections on analysis. The diagnosis was either concordant or discordant. The diagnostic … Show more

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“…At some medical centers, intra-operative consultations for resection samples are processed in a frozen section procedure, which allows for more rapid diagnosis of the tissue specimens while trading off diagnostic accuracy when compared to fixation in formalin. 551 , 552 Frozen section samples will be rapidly frozen after the proceeding grossing step, therefore they arrive in the lab unprocessed and remain unprocessed until after grossing, undergoing the aforementioned cold ischemia changes in the meantime.…”
Section: Appendixmentioning
confidence: 99%
See 1 more Smart Citation
“…At some medical centers, intra-operative consultations for resection samples are processed in a frozen section procedure, which allows for more rapid diagnosis of the tissue specimens while trading off diagnostic accuracy when compared to fixation in formalin. 551 , 552 Frozen section samples will be rapidly frozen after the proceeding grossing step, therefore they arrive in the lab unprocessed and remain unprocessed until after grossing, undergoing the aforementioned cold ischemia changes in the meantime.…”
Section: Appendixmentioning
confidence: 99%
“…Frozen section samples are rapidly frozen using a freezing medium such as liquid nitrogen, dry ice, or isopentane. 174 , 175 , 551 , 552 After freezing, the tissue is cut using a microtome and fixed immediately, most often with formalin. 174 , 175 Slides are then stained and covered with a glass coverslip and stored at 80 °C.…”
Section: Appendixmentioning
confidence: 99%