In recent decades many forests in Slovakia, especially those in mountain basins, have been devastated by wind or snow calamities. Hence, the main aim of this paper is to analyze land use and estimate the changes in runoff from the Boca and Ipoltica river basins in Slovakia for historical (1990 and 2006) and present land use (2012). The changes in runoff are presented as changes in design floods. For estimating the design floods, the curve number method was used. The values of the design floods on both of these river basins have increased due to deforestation.