Analysis of image sharpness reproducibility on a novel engineered micro-CT scanner with variable geometry and embedded recalibration software

Panetta, Daniele; Belcari, Nicola; Guerra, A. Del; Bartolomei, A.; Salvadori, Piero A.

doi:10.1016/j.ejmp.2011.03.006

Cited by 31 publications

(22 citation statements)

References 17 publications

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“…The three-dimensional morphometric analysis of whole femurs was performed using a compact micro-CT scanner with variable geometry at the Institute of Clinical Physiology (IFC-CNR) in Pisa, Italy (Panetta et al, 2012). A total of 720 projections at magnification 2.6 were acquired over 3601 of sample rotation on axial axis with the following parameters: 50 kV, 1 mm Al filtration, 0.6 mA, 0.6 s/projection for a total scan time of 7 min per sample.…”

Section: 4mentioning

confidence: 99%

Effects of long time exposure to simulated micro- and hypergravity on skeletal architecture

Canciani

Ruggiu

Giuliani

et al. 2015

Journal of the Mechanical Behavior of Biomedical Materials

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Section: 4mentioning

confidence: 99%

Effects of long time exposure to simulated micro- and hypergravity on skeletal architecture

Canciani

Ruggiu

Giuliani

et al. 2015

Journal of the Mechanical Behavior of Biomedical Materials

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“…An in-house developed micro-CT scanner installed at IFC-CNR, Pisa, was used [28]. All the tomographic acquisitions were made with 720 projections over 360 degrees, for a total scan time of 54 min and a total exposure of 2268 mAs.…”

Section: Micro-ctmentioning

confidence: 99%

Computerized methodology for micro-CT and histological data inflation using an IVUS based translation map

Athanasiou

Rigas

Sakellarios

et al. 2015

Computers in Biology and Medicine

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“…Some scanners now provide zoom-in capability and variable geometry [33]. With such changes, geometric calibration is required to maximize spatial resolution in the reconstructed image data.…”

Section: Technologymentioning

confidence: 99%

Micro-CT of rodents: State-of-the-art and future perspectives

2014

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Micron-scale computed tomography (micro-CT) is an essential tool for phenotyping and for elucidating diseases and their therapies. This work is focused on preclinical micro-CT imaging, reviewing relevant principles, technologies, and applications. Commonly, micro-CT provides high-resolution anatomic information, either on its own or in conjunction with lower-resolution functional imaging modalities such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT). More recently, however, advanced applications of micro-CT produce functional information by translating clinical applications to model systems (e.g. measuring cardiac functional metrics) and by pioneering new ones (e.g. measuring tumor vascular permeability with nanoparticle contrast agents). The primary limitations of micro-CT imaging are the associated radiation dose and relatively poor soft tissue contrast. We review several image reconstruction strategies based on iterative, statistical, and gradient sparsity regularization, demonstrating that high image quality is achievable with low radiation dose given ever more powerful computational resources. We also review two contrast mechanisms under intense development. The first is spectral contrast for quantitative material discrimination in combination with passive or actively targeted nanoparticle contrast agents. The second is phase contrast which measures refraction in biological tissues for improved contrast and potentially reduced radiation dose relative to standard absorption imaging. These technological advancements promise to develop micro-CT into a commonplace, functional and even molecular imaging modality.

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Analysis of image sharpness reproducibility on a novel engineered micro-CT scanner with variable geometry and embedded recalibration software

Cited by 31 publications

References 17 publications

Effects of long time exposure to simulated micro- and hypergravity on skeletal architecture

Effects of long time exposure to simulated micro- and hypergravity on skeletal architecture

Computerized methodology for micro-CT and histological data inflation using an IVUS based translation map

Micro-CT of rodents: State-of-the-art and future perspectives

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