Analysis of Inflammatory Cells in Osseointegration of CpTi Implant Radiated by Low Level Laser Therapy

Abstract

Background: Dental implants provide a unique treatment modality for the replacement of a lost dentition .This is accomplished by the insertion of relatively an inert material (a biomaterial) into the soft and hard tissue of the jaws, there by providing support and retention for dental prostheses. Low level laser therapy (LLLT) is an effective tool used to prompt bone repair and remodeling, this has referred to the biostimulation effect of LLLT. The Aim of this study was to evaluate the effects of inflammatory cells on osseointegration of CpTi implant irradiated by low level laser. Materials and Methods: thirty two adult New Zealand white rabbits, received titanium implants were inserted in the tibia. The right side is considered as experimental groups and the left side considered as control groups. Low power diode laser (GaAlAs) with wave length (904nm) and (5mW)power applicated with the right implants. The sample divided into four groups, eight rabbits were sacrificed at four interval 4days, 1 weeks, 2weeks, and 6weeks respectively. Histological and inflammatory analyses were done for each interval. Results: Histological examination showed acceleration of bone formation and more rapid healing process in the screw implant with laser irradiation than in the control implant .inflammatory analysis showed dramatic decrease with the presence of laser irradiation especially with advancing time. Conclusion: This study illustrated that the inflammatory cells were reduced in osseointegration of dental implant treated with LLLT.

Radioprotective role of amifostine on osteointegration of titanium implants in the tibia of rats

“…Therefore, it significantly protects the bone quality through preserving osseous regeneration and repair capacity. Similarly, the radioprotective effect of amifostine on bone-forming cells has been previously shown to increase bone regeneration capacity [ 28 ]. Besides, a prior study has determined the effects of radiation treatment on the mineral composition of the mandible [ 8 ].…”