Analysis of spatial diffusion of ferric ions in PVA-GTA gel dosimeters through magnetic resonance imaging

Marrale, Maurizio; Collura, Giorgio; Gallo, Salvatore; Nici, S.; Tranchina, Luigi; Abbate, B.; Marineo, Sandra; Caracappa, Santo; D’Errico, Francesco

doi:10.1016/j.nimb.2017.02.008

Cited by 38 publications

(27 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The PVA Mowiol ® 18-88, produced by Sigma-Aldrich, was employed in this experiment. The complete dissolution of Mowiol ® 18-88 in water can be easily obtained in approximately 40 minutes at 70°C, without the use of proper equipment required for other PVA compounds, as autoclave [30,38] or open vessel microwave digestion [32,37]. The other components used to prepare the PVA-GTA Fricke gel dosimeters were: Ferrous ammonium sulfate hexahydrate (FAS, Carlo Erba), Xylenol Orange tetrasodium sodium salt (XO, Riedel-de Haën), Glutaraldehyde (GTA, Sigma-Aldrich), and Sulfuric acid (SA, Sigma-Aldrich).…”

Section: Samples Preparationmentioning

confidence: 99%

Temperature behavior of radiochromic poly(vinyl-alcohol)-glutaraldehyde Fricke gel dosimeters in practice

Gallo

Lizio

Monti

et al. 2020

J. Phys. D: Appl. Phys.

Self Cite

View full text Add to dashboard Cite

The use of synthetic gel matrices prepared with poly(vinyl-alcohol) (PVA) cross-linked by glutaraldehyde (GTA) contributed to enhance the interest toward radiochromic Fricke gel (FG) dosimeters. As it occurs in several chemical dosimeters, the response of PVA-GTA Fricke gels could be affected by temperature. Aim of this work is to study the dependence of the dosimetric properties of PVA-GTA Fricke gel dosimeters both on the irradiation temperature and on temperature changes possibly occurring between the irradiation and readout phases. Such effects were investigated by means of magnetic resonance imaging (MRI) and optical absorbance (OA) measurements.

show abstract

Section: Samples Preparationmentioning

confidence: 99%

Temperature behavior of radiochromic poly(vinyl-alcohol)-glutaraldehyde Fricke gel dosimeters in practice

Gallo

Lizio

Monti

et al. 2020

J. Phys. D: Appl. Phys.

Self Cite

View full text Add to dashboard Cite

show abstract

“…We performed the experiments using dosimeters prepared with a gel matrix composed by synthetic hydrogels based on poly(vinyl-alcohol) (PVA) chemical cross-linked with glutaraldehyde (GTA) and loaded with XO. Such composition proved to be characterized by a diffusion rate of ferric ions significantly lower that what achievable with natural gel matrices like gelatin from porcine skin and agarose [39,40]. For this reason, the interest toward PVA-GTA Fricke gel dosimetry is gaining importance, as attested by the increasing literature about this topic [41][42][43][44][45][46][47].…”

Section: Introductionmentioning

confidence: 99%

Effect of ionizing radiation on the colorimetric properties of PVA-GTA Xylenol Orange Fricke gel dosimeters

et al. 2021

Self Cite

View full text Add to dashboard Cite

This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

show abstract

“…However, the ferrous ions (Fe 2+ ) in Fricke gels are oxidized to ferric ions (Fe 3+ ) upon irradiation, which leads to the poor stability of spatial dose information storage, owing to diffusion of Fe 3+ [ 17 ]. Many research studies have focused on reducing ion diffusion in Fricke gels, including optimization of gel matrix materials [ 18 , 19 , 20 ], design of Fe 3+ selective ligand [ 21 , 22 , 23 , 24 ], improvement of cross-linking method for gels [ 25 , 26 ], and addition of nano-sized clay particles [ 27 , 28 ]. In addition, strategies based on spatial confinement to suppress diffusion have also been proposed.…”

Section: Introductionmentioning

confidence: 99%

Low-Diffusion Fricke Gel Dosimeters with Core-Shell Structure Based on Spatial Confinement

Zhang

Zeng

et al. 2021

Materials

View full text Add to dashboard Cite

The diffusion of ferric ions is an important challenge to limit the application of Fricke gel dosimeters in accurate three-dimensional dose verification of modern radiotherapy. In this work, low-diffusion Fricke gel dosimeters, with a core-shell structure based on spatial confinement, were constructed by utilizing microdroplet ultrarapid freezing and coating technology. Polydimethylsiloxane (PDMS), with its excellent hydrophobicity, was coated on the surface of the pellets. The concentration gradient of the ferric ion was realized through shielding half of a Co-60 photon beam field size, and ion diffusion was measured by both ultraviolet-visible spectrophotometry and magnetic resonance imaging. No diffusion occurred between the core-shell pellets, even at 96 h after irradiation, and the diffusion length at the irradiation boundary was limited to the diameter (2–3 mm) of the pellets. Furthermore, Monte Carlo calculations were conducted to study dosimetric properties of the core-shell dosimeter, which indicated that a PDMS shell hardly affected the performance of the dosimeter.

show abstract

Analysis of spatial diffusion of ferric ions in PVA-GTA gel dosimeters through magnetic resonance imaging

Cited by 38 publications

References 49 publications

Temperature behavior of radiochromic poly(vinyl-alcohol)-glutaraldehyde Fricke gel dosimeters in practice

Temperature behavior of radiochromic poly(vinyl-alcohol)-glutaraldehyde Fricke gel dosimeters in practice

Effect of ionizing radiation on the colorimetric properties of PVA-GTA Xylenol Orange Fricke gel dosimeters

Low-Diffusion Fricke Gel Dosimeters with Core-Shell Structure Based on Spatial Confinement

Contact Info

Product

Resources

About