Analysis of sterol compounds from Sambucus ebulus

Bubulica, Maria-Viorica; Chirigiu, Liviu; Popescu, Mariana; Simionescu, Andreea; Anoaica, Gabriel; Popescu, Anca

doi:10.1007/s10600-012-0297-y

Cited by 14 publications

(14 citation statements)

References 11 publications

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“…Several studies revealed that SE leaves comprise various compounds such as flavonoids, polyphenols, triterpenes, tannins, iridoids, phytosterols, lectins, sugars, fibers, vitamins, and minerals [5][6][7][8]. The main therapeutic benefits of SE extracts are related to their antioxidant and anti-inflammatory properties, making them valuable sources for food, cosmetic and pharmaceutical industries, as well as medicine.…”

Section: Introductionmentioning

confidence: 99%

Polyphenolic Extract from Sambucus ebulus L. Leaves Free and Loaded into Lipid Vesicles

et al. 2019

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The paper deals with the preparation and characterisation of hydroalcoholic polyphenolic extract from Sambucus ebulus (SE) leaves that was further loaded into three-types of lipid vesicles: liposomes, transfersomes, and ethosomes, to improve its bioavailability and achieve an optimum pharmacological effect. For Sambucus ebulus L.-loaded lipid vesicles, the entrapment efficiency, particle size, polydispersity index and stability were determined. All prepared lipid vesicles showed a good entrapment efficiency, in the range of 75–85%, nanometric size, low polydispersity indexes, and good stability over three months at 4 °C. The in vitro polyphenols released from lipid vehicles demonstrated slower kinetics when compared to the free extract dissolution in phosphate buffer solution at pH 7.4. Either free SE extract or SE extract loaded into lipid vesicles demonstrated a cytoprotective effect, even at low concentration, 5 ug/mL, against hydrogen peroxide-induced toxicity on L-929 mouse fibroblasts’ cell lines. However, the cytoprotective effect depended on the time of the cells pre-treatment with SE extract before exposure to a hydrogen peroxide solution of 50 mM concentration, requiring at least 12 h of pre-treatment with polyphenols with radical scavenging capacity.

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Section: Introductionmentioning

confidence: 99%

Polyphenolic Extract from Sambucus ebulus L. Leaves Free and Loaded into Lipid Vesicles

et al. 2019

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“…In addition, Sambucus plants accumulate wide range of secondary metabolites, as flavonoids (Yesilada et al, 2014;Zahmanov et al, 2015), anthocyanins (Duymus et al, 2014), phytosterols (Bubulica et al, 2012), triterpenes (Zahmanov et al, 2015) and iridoid glycosides (Pieri et al, 2009), among others. Sambucus plants, however, also accumulate cyanogenic glycosides, as sambunigrin, prunasin, holocalin (Dellagreca et al, 2000).…”

Section: Introductionmentioning

confidence: 99%

Metabolic differentiations of dwarf elder by NMR-based metabolomics

Zahmanov

Alipieva

Simova

et al. 2015

Phytochemistry Letters

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“…The results of the GC-MS analysis of volatile compounds [18,19] from the tincture obtained by relating the retention time of the gas chromatograms of the data provided by the mass spectrometer, led to the observation that volatile ethyl-methyl carbonate is present in both tinctures (table 4). In literature it is noted that vegetable extracts that contain anthocyanins and phenolic acids have potential antibacterial on the bacteria Escherichia coli and Proteus vulgaris, which causes frequently urinary infections and sepsis [20].…”

Section: Resultsmentioning

confidence: 99%

Determination of Polyphenol and Flavonoid Profiles and Testing the Antibacterial Effect of Acanthus longifolius Comparative with Vaccinium myrtillus

Varut¹,

Rotaru²

2017

Rev. Chim.

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From our research we noticed that Acanthi balcanici herba (ABH) contains luteolin and quercetol and Myrtillus fructus (M-fr) contains chlorogenic acid, apigenol and rutoside. ABH has no antibacterial effect on any species tested, completely cancel the therapeutic effect of three drugs (amoxicillin + clavulanic acid, levofloxacin, amikacin) and have no significant effect on the other two antibiotics (cefotaxime and ceftazidime) when they are associated. All bacterial species were sensitive to M-fr and the extract has synergistic effect in combination with levoflaxacin, amikacin and cefotaxime.

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Analysis of sterol compounds from Sambucus ebulus

Cited by 14 publications

References 11 publications

Polyphenolic Extract from Sambucus ebulus L. Leaves Free and Loaded into Lipid Vesicles

Polyphenolic Extract from Sambucus ebulus L. Leaves Free and Loaded into Lipid Vesicles

Metabolic differentiations of dwarf elder by NMR-based metabolomics

Determination of Polyphenol and Flavonoid Profiles and Testing the Antibacterial Effect of Acanthus longifolius Comparative with Vaccinium myrtillus

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