Analysis of the association between polypharmacy and socioeconomic position among elderly aged ≥77 years in Sweden

Haider, Syed Imran; Johnell, Kristina; Thorslund, Mats; Fastbom, Johan

doi:10.1016/j.clinthera.2008.02.010

Cited by 100 publications

(124 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is mainly due to increase of the aging population, an increasing prevalence of chronic heart diseases and of risk factors for atrial fibrillation, such as diabetes mellitus. 40 In agreement with a previous Swedish study, 9 both genders had a significantly higher use of analgesics in 2007 as compared to 1987. An increasing trend of opioid utilization has also been reported from the United States.…”

Section: Use Of Drugs According To Atc Groupssupporting

confidence: 81%

“…2,8 In Sweden more than 40% of the population aged 77+ years use more than 5 drugs concurrently. 9 Concurrent use of many drugs (polypharmacy) 10 is common in older adults 11 and is a risk factor for adverse drug reactions and drug-drug interactions (DDIs). 8,[11][12][13] In addition, due to altered pharmacokinetics and pharmacodynamics in old age, elderly patients are particularly sensitive to drugs and at increased risk of adverse drug reactions.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Time trends in 20 years of medication use in older adults: Findings from three elderly cohorts in Stockholm, Sweden

Craftman

Johnell

Fastbom

et al. 2016

Archives of Gerontology and Geriatrics

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Use Of Drugs According To Atc Groupssupporting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

Time trends in 20 years of medication use in older adults: Findings from three elderly cohorts in Stockholm, Sweden

Craftman

Johnell

Fastbom

et al. 2016

Archives of Gerontology and Geriatrics

Self Cite

View full text Add to dashboard Cite

show abstract

“…Another factor that affected daily drug use of the elderly was marital status. Similar to our study, Haider et al (43) found a significant correlation between the number of medications taken daily and marital status.…”

Section: Discussionsupporting

confidence: 81%

“…Chronic disease duration of the subjects according to sociodemographic characteristics (n=472) same study also determined that the number of drugs taken by the elderly with a low educational level was 4.6 and that as their educational level increased, this number decreased. Hence, social security coverage was associated with medication use (43). Kim et al (46) assessed predominately housewives and retirees and confirmed that social security coverage was associated with multiple medication use, and the elderly with this insurance were three times more likely to be associated with polypharmacy.…”

Section: Discussionmentioning

confidence: 99%

The Prevalence of Chronic Diseases and Drug Use Among Geriatric Cases in Ardesen County of Rize Province

Sarımehmet¹,

Hintistan²

2017

Bezmialem Science

View full text Add to dashboard Cite

ÖZAmaç: Bu çalışmanın amacı, Rize ili Ardeşen ilçesindeki geriatrik olgular arasında kronik hastalık sıklığı ve ilaç kullanımlarını değerlendirmektir. Yöntemler: Kesitsel ve tanımlayıcı ilişki arayıcı nitelikteki çalış-ma, Mart-Haziran 2014 tarihleri arasında 482 yaşlı bireyle yapıl-dı. Veriler, yüz yüze görüşme tekniği tekniği kullanılarak Kişisel Bilgi Formu ile toplandı. Veriler, yüzdelik ve Ki kare testi ile değerlendirildi. Bulgular: Bu çalışmada, yaşlıların %52,9'u 65-74 yaş grubunda ve %97,9'u kronik hastalığa sahiptir. Yaşlıların en sık karşılaş-tığı kronik hastalık, kardiyovasküler sisteme ait hastalıklardır (%74,3). Yaşlıların %49'u günde 3-4 adet ilaç kullanmakta ve %99,2'si bu ilaçları oral yoldan almaktadır. Ancak kullanılan bu ilaçlar, yaşlıların %24,3'ünde gastrointestinal yakınmalara neden olmaktadır. Yaşlıların %44,6'sının ilaç kullanımları ile ilgili en zorlayıcı durumu ilaç almayı unutmaktır. Yaşlıların kronik hastalık süresini cinsiyet, yaş, meslek, aylık gelir düzeyi ve sosyal gü-vence etkilerken; günlük kullandıkları ilaç sayısını yaş, medeni durum, eğitim düzeyi, meslek, sosyal güvence ve birlikte yaşanı-lan kişiler etkilemektedir (p<0,05). Sonuç: Kronik hastalık gelişimi ve bu hastalıkların tedavisinde kullanılan ilaçlarla ilgili risk faktörlerini azaltmaya yönelik önle-yici tedbirlere odaklanılmalıdır. Anahtar Kelimeler: Kronik hastalık, ilaç kullanımı, yaşlı, sıklık ABSTRACTObjective: This study aimed to evaluate the prevalence of chronic diseases and drug use among geriatric cases in Ardesen County of Rize Province. Methods: A cross-sectional and descriptive correlational study including 482 elderly was conducted between March and June 2014. Data were collected using the personal information form via faceto-face interviews. All data were analyzed as percentages using the chi-square test. Results: In this study, 97.9% of the elderly had chronic diseases and 52.9% were in the 65-74-year age group. The most frequent chronic diseases included those of the cardiovascular system (74.3%). In addition, 49% of the group used three or four medications daily, and 99.2% took their medications orally. However, these medications caused gastrointestinal problems for 24.3% of the subjects. For 44.6% of the elderly, the most challenging aspect regarding their medications was forgetting to take them. Sex, age, profession, monthly income level, and social security status affected the duration of the chronic diseases of the elderly, whereas age, marital status, educational level, profession, social security coverage, and the people with whom they lived affected the number of medications used daily by this group (p<0.05). Conclusion: Preventive measures should focus on reducing risk factors related to the development of chronic diseases and the drugs used to treat them.

show abstract

“…The number of medical appointments is a wellknown indicator of polypharmacy (Haider et al, 2008;Rozenfeld, Fonseca, Acurcio, 2008), nevertheless in clinical practice this evidence deserves a critical evaluation of the rationality of pharmacotherapy, since in geriatrics a physiological alteration inherent to the ageing process can be confounded with a health problem, leading to an unnecessary prescription.…”

Section: Discussionmentioning

confidence: 99%

Pharmacoepidemiological profile and polypharmacy indicators in elderly outpatients

Baldoni

Ayres

Martinez

et al. 2013

Braz. J. Pharm. Sci.

View full text Add to dashboard Cite

This cross-sectional study was carried out with 1000 elderly outpatients assisted by a Basic Health District Unit (UBDS) from the Brazilian Public Health System (SUS) in the municipality of Ribeirão Preto. We analyzed the clinical, socioeconomic and pharmacoepidemiological profile of the elderly patients in order to identify factors associated with polypharmacy amongst this population. We used a truncated negative binomial model to examine the association of polypharmacy with the independent variables of the study. The software SAS was used for the statistical analysis and the significance level adopted was 0.05. The most prevalent drugs were those for the cardiovascular system (83.4%). There was a mean use of seven drugs per patient and 47.9% of the interviewees used ≥7 drugs. The variables that showed association with polypharmacy (P value < 0.01) were female gender, age >75 years, self-medication, number of health problems, number of medical appointments, presence of adverse drug events, use of over-the-counter drugs, use of psychotropic drugs, lack of physical exercise and use of sweeteners. The exposition to all these factors justified the high prevalence of polypharmacy amongst the interviewees. These results showed the need to adopt clinical intervention and educational and managerial measures to analyze and promote rationality in the use of drugs amongst the elderly users of SUS. Uniterms:Pharmacoepidemiology. Elderly/use of drugs. Polypharmacy. Drugs/rational use. Public Health System. Este estudo transversal foi realizado por meio de entrevistas com 1000 idosos atendidos em uma Unidade Básica Distrital de Saúde (UBDS) do Sistema Único de Saúde (SUS) no município de Ribeirão Preto. Analisou-se o perfil clínico, socioeconômico e farmacoepidemiológico a fim de identificar os fatores associados à polifarmácia nessa população. Utilizou-se um modelo binomial negativo truncado para análise da associação da polifarmácia com as variáveis independentes do estudo. O software SAS foi utilizado para a análise estatística. O nível de significância adotado foi de 0,05. Os fármacos com maior prevalência de uso foram do sistema cardiovascular (83,4%). Observou-se média de, aproximadamente, sete fármacos por paciente e 47,9% dos entrevistados usavam >7 fármacos. As variáveis que apresentaram associação com a polifarmácia (p< 0,01) foram: mulheres, idade (>75 anos), automedicação, quantidade de problemas de saúde, número de consultas médicas, uso de medicamentos isentos de prescrição médica, uso de psicotrópicos, não realização de exercícios físicos e uso de adoçante. A exposição a todos esses fatores justifica a alta prevalência de polifarmácia entre os entrevistados. Os resultados mostraram a necessidade de adotar medidas de intervenção clínica e educacional e gerencial para analisar e promover a racionalização do uso de fármacos entre os idosos usuários do SUS.Unitermos: Farmacoepidemiologia. Idoso/uso de medicamentos. Polifarmácia. Medicamentos/uso racional. Sistema Público de Saúde.

show abstract

Analysis of the association between polypharmacy and socioeconomic position among elderly aged ≥77 years in Sweden

Cited by 100 publications

References 30 publications

Time trends in 20 years of medication use in older adults: Findings from three elderly cohorts in Stockholm, Sweden

Time trends in 20 years of medication use in older adults: Findings from three elderly cohorts in Stockholm, Sweden

The Prevalence of Chronic Diseases and Drug Use Among Geriatric Cases in Ardesen County of Rize Province

Pharmacoepidemiological profile and polypharmacy indicators in elderly outpatients

Contact Info

Product

Resources

About