Analysis of the Chemical Composition and Antimicrobial Activity of the Essential Oil from<i>Rhamnus alaternus</i>

Chouitah, O.; Meddah, B.; Aoues, Abdelkader

doi:10.1080/22311866.2012.10719138

Cited by 1 publication

(2 citation statements)

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“…Campbell et al, (2019) reported essential oils from the leaves of R. prinoides of which 4-hydroxy-4methyl-2-pentanone and ethyl 4-ethoxybenzoate score more than 85% and exhibited significant anti-biofilm activity (113). In a related study, Chouitah et al, (2012) (GOT),Glutamic pyruvic transaminase (GPT) and total bilirubin and significantly attenuated the deleterious histopathologic changes in the liver after carbon tetrachloride (CCl4)-intoxication (14).…”

Section: Essential Oilsmentioning

confidence: 99%

“…The TOF extracts showed activities against S. aureus, E. faecalis, E. coli, S. enteritidis and S. typhimurium with MIC values of 120 μg/mL,175 μg/mL, 1.75 mg/mL, 125 μg/mL and 62.5 μg/mL, respectively, while the ethyl acetate extract exhibited with MIC values of 70 μg/mL, 150 μg/mL, 3.75 mg/mL, 100 μg/mL and 175 μg/mL, respectively (118). Chouitah et al, (2012) evaluated antibacterial activities of essential oils of R.alaternus leaves against P. aeroginosa, E. coli and S. typhimurium using the paper disc diffusion method. The essential oils exhibited activities with zones of inhibition 8, 17 and 15 mm, respectively (114).…”

Section: Anti-inflammatory Activitymentioning

confidence: 99%

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Traditional Medicinal Uses, Phytochemicals, and Pharmacological Activities of Genus Rhamnus: A review

Nigussie

Melak

Endale

2021

Journal of the Turkish Chemical Society Section A: Chemistry

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The genus Rhamnus belongs to the Rhamnaceae family, which contains approximately 137 species, traditionally used as folk medicine in East Asia, North and South America, and subtropical regions of Africa. The genus is used traditionally to treat diseases such as cancer, wound, jaundice, hepatitis, gonorrhea, laxative, hypertension, malaria, stomach ache, snake bite and diarrhea. Anthraquinones and flavonoids are the most cited compounds from the genus of which polyphenols were abundant with tremendous antioxidant, wound healing and antiinflammatory activities. Pharmacological activity evaluation of the extracts and isolated compounds revealed anti-inflammatory, antioxidant, antimalarial, antibacterial, anti-mutagenic, anti-genotoxic, hepatoprotective, anticancer, and antiproliferative activity. The genus afforded drug leads such as 6-methoxysorigenin (12) and prinoidin ( 23) with anti-tyrosinase and cytotoxicity, respectively, as well as antioxidant drug leads such as Kaempferol-3-O-β-rhamninoside (31) rhamnetin-3-O-β-isorhamninoside (37) and isotorachrysone (55). The present review endeavors to provide a comprehensive and up to date compilation of documented traditional medicinal uses, phytochemicals and pharmacological activities of the genus and provided valuable information in support of its uses as an alternative medicine for future healthcare practice.

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