Analysis of the Relationship Between Serum Zinc Values and Allergic Rhinitis Parameters in Patients with Allergic Rhinitis

Abstract

Background/Aim: Zinc is an significant trace element that acts an active part in the immune system and is associated with allergic inflammatory diseases. In the literature, various results have been shown in studies on the coexistence of serum zinc level and allergic rhinitis. The objective of this research was to analyze the intercourse among serum zinc levels and whole blood parameters in allergic rhinitis (AR). Method:In this research, patients were appraised in consistency with the instruction for "Allergic Rhinitis and Its Effect on Asthma". Serum total Ig E, C-reactive protein grades in the AR group and leukocyte, neutrophil, eosinophil and lymphocyte counts, neutrophil/lymphocyte, eosinophil/lymphocyte, platelet/lymphocyte ratio and serum zinc values in whole-blood parameters of all cases were analyzed and contrasted between the AR and control groups.Findings: Neutrophil and eosinophil counts and eosinophil/lymphocyte ratio were presented as significantly superior in the AR category than in the control category (p<0.05). Serum zinc values in the AR category were remarkably underneath than those in the control category (p<0.05). In the univariate model, it was noticed that the eosinophil and zinc values had a significant-independent differential effect in distinguishing the AR and control category patients (p< 0.05). Conclusion:Serum zinc level, neutrophil and eosinophil count, eosinophil/lymphocyte ratio in the blood are practical biochemical indicators that can be used to recognition, treatment, together with following-up of cases with allergic rhinitis. It is assumed that with the support of zinc deficiency, important clinical benefits can be achieved in anti-allergic treatment.