Analysis of the Volatile Compounds in <i>Senecio Scandens</i> Buch-Ham by Gas Chromatography—Tandem Mass Spectrometry Based on Diversified Scan Technologies

Li, Sensen; Su, Yue; Guo, Yinlong

doi:10.1255/ejms.1142

Cited by 10 publications

(5 citation statements)

References 23 publications

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“…[1][2][3][4] Qualitative approaches comprising mass spectral search, retention index and diversified scan technologies were utilized to identify volatile compounds. [5][6][7][8] The combination of these approaches can provide satisfactory identification results for volatile compounds including some trace-level components. However, the rapid development and wide application of high-resolution-timeof-flight-mass spectrometry (HR-ToF-MS) in the last decade allows us to look at the qualitative problem from a different point of view.…”

Section: European Journal Of Mass Spectrometrymentioning

confidence: 99%

Application of Gas Chromatography-Quadrupole-Time-of-Flight-Mass Spectrometry for Post-Target Analysis of Volatile Compounds in Fructus Amomi

Kang

Zhang

et al. 2013

Eur J Mass Spectrom (Chichester)

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A post-target analysis method based on gas chromatography coupled to a high-resolution quadrupole time-of-flight mass analyzer is applied for the investigation of volatile compounds in Fructus Amomi. A series of narrow window extracted ion chromatograms at selected characteristic ions were performed. Chromatographic peaks with the same retention time in different extracted ion chromatograms was used to screen out the candidate compound. Identification was achieved by the accurate masses of several characteristic ions and the retention index of the peak. Forty six compounds, including 12 monoterpene compounds, were identified by conventional static headspace gas chromatography mass spectrometry and another six monoterpene compounds were found and identified by the post-target method. Post-target analysis is a useful strategy in qualitative research of natural products.

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Section: European Journal Of Mass Spectrometrymentioning

confidence: 99%

Application of Gas Chromatography-Quadrupole-Time-of-Flight-Mass Spectrometry for Post-Target Analysis of Volatile Compounds in Fructus Amomi

Kang

Zhang

et al. 2013

Eur J Mass Spectrom (Chichester)

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“…Despite this great diversity, only about one hundred and sixty papers devoted to the study of the essential oils and volatile compounds of Senecio species (which was the former genus of P. herzogii ) are reported in the SciFinder ® database [ 13 ]. Less than ten of them show the presence of low percentages (<2%) of thymol methyl ether and only three the occurrence of carvacrol methyl ether ( Table 2 ) [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ]. Surprisingly, one paper mentions the ambiguous o -methyl thymol as an identified compound in the S. scandens essential oil [ 19 ].…”

Section: Resultsmentioning

confidence: 99%

“…Less than ten of them show the presence of low percentages (<2%) of thymol methyl ether and only three the occurrence of carvacrol methyl ether ( Table 2 ) [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ]. Surprisingly, one paper mentions the ambiguous o -methyl thymol as an identified compound in the S. scandens essential oil [ 19 ]. In South America, the reported studies indicate that hydrogenated monoterpenes constitute the most important part of the identified compounds in Senecio essential oils.…”

Section: Resultsmentioning

confidence: 99%

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Essential Oils from Bolivia. XV. Herzogole, an Original Monoterpene Benzodioxole from an Essential Oil from Pentacalia herzogii (Cabrera) Cuatrec

St-Gelais¹,

Maldonado

Saavedra

et al. 2021

Molecules

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Over 15 years, with the support of a Canadian funding agency, the Universidad Mayor de San Simón, in Bolivia, undertook a large survey of aromatic plants of the South American country. More than a hundred species were studied under various aspects, including the production and characterization of essential oils. As part of this survey, the chemical composition of an essential oil sample obtained from Pentacalia herzogii (Asteraceae) growing wild in the High Valley region of the department of Cochabamba was determined by a combination of GC and GC-MS measurements. α-Pinene was the main constituent of this essential oil (34%), accompanied by limonene (22%) and germacrene D (7.5%) as well as an important fraction of methoxylated monoterpenoids. They were mainly isomers of thymol methyl ether, accounting for 13% of the chromatogram. A new quantitatively important compound (9%) was identified through NMR and chemical synthesis as 4-isopropyl-6-methylbenzo[d][1,3]dioxole, and designated herzogole, alongside the minor related compound 1-isopropyl-2,3-dimethoxy-5-methylbenzene. The monoterpene benzodioxole featured a distinctive green-phenolic aroma which could raise interest for fragrance use. Since these compounds were not known naturally, a biosynthetic mechanism of their formation was proposed and put in perspective to illustrate the metabolic originality of P. herzogii.

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“…串联质谱始于 20 世纪 70 年代, 至今已经成功应用于复杂样品痕量成分分析、未知化合物结构确证及离子裂解规律的研究 [14～17] . 串联质谱能显著增强选择性, 提高检出限, 多种串联质谱扫描技术的联合应用(同位素串联质谱、母离子扫描、子离子扫描、中性丢失扫描)提高了化合物定性的准确性 [18,19] . 高分辨质谱能在一次分析中获得一级全扫描准确质量, 这使得研究者可采用后目标分析法从总离子流图中提取所需信息以满足分析需求.…”

Section: 引言unclassified

Post-target Analysis for the Volatile Compounds from SaltyAlpinia oxyphyllae Fructuswith Headspace-gas Chromatography-quadrupole/time of Flight Mass Spectrometry

陈房姣¹,

苏越²,

郭寅龙³

2014

Acta Chim. Sinica

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Post-target analysis is a superior method for qualitative analysis. This method can make a rapid, accurate and wide-scope screening for non-target and target compounds, and it has been used widely in the metabonomics, environmental analysis and pesticide residues. With post-target method to analysis non-target compounds, retention index, accurate mass and library were applied to investigate non-target analytes and then a total of 119 compounds were identified. Within those 119 compounds, there are different kinds of compounds, such as aliphatic aldehyde, aromatic ketone, aromatic aldehyde, monoterpene and its oxide, sesquiterpenes and its oxide and so on. Eremophilene is the best peak ingredient, p-cymene, aromadendrene, nootkatone and δ-cadinene are the main ingredients. Besides, nootkatone is the main active ingredient according to previous pharmacology research. Narrow mass window extracted ion chromatograms (nw-XIC) can decrease background noise greatly and improve the signal-to-noise rate. Hence, the trace level or co-elution compounds can be identified. With the post-target analytical method for target analytes, we calculated retention time from retention index of target compounds, and then nw-XIC (mass window 0.02 Da) was carried out. Four characteristic ions of target compounds were extracted to get extracted ion chromatograms at calculated retention time. As peaks at calculated retention time had the same chromatographic behavior, we identified three target compounds: nootkatol, α-cyperone and perillaldehyde. Tandem mass technology has been widely used since its introduction in the 1970s, it was used in trace analysis, chemical reaction mechanistic studies and propose the fragmentation pattern of compounds. In this paper, we got first-stage mass spectra and second-stage mass spectra data in one experiment. Moreover, we could obtain accurate mass of precursor ion and product ion from second-stage mass spectra at the same time, then we inferred the MS fragmentation pattern of compounds. This method is more simple, convenient and accurate than the traditional tandem mass spectrometry. Myrtenal was identified in this post-target way. Post-target analytical method can distinguish compounds from complex matrix samples as many as possible. This method solves the problems of co-elution and high background and can be used to investigate the medicine's pharmacology and toxicology mechanism. Keywords post-target analysis; nw-XIC; tandem mass spectrometry; accurate mass measurement; retention index; salty Alpinia oxyphylla Miq.

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Analysis of the Volatile Compounds in Senecio Scandens Buch-Ham by Gas Chromatography—Tandem Mass Spectrometry Based on Diversified Scan Technologies

Cited by 10 publications

References 23 publications

Application of Gas Chromatography-Quadrupole-Time-of-Flight-Mass Spectrometry for Post-Target Analysis of Volatile Compounds in Fructus Amomi

Application of Gas Chromatography-Quadrupole-Time-of-Flight-Mass Spectrometry for Post-Target Analysis of Volatile Compounds in Fructus Amomi

Essential Oils from Bolivia. XV. Herzogole, an Original Monoterpene Benzodioxole from an Essential Oil from Pentacalia herzogii (Cabrera) Cuatrec

Post-target Analysis for the Volatile Compounds from SaltyAlpinia oxyphyllae Fructuswith Headspace-gas Chromatography-quadrupole/time of Flight Mass Spectrometry

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