Analysis on the pathogenic fungi in patients with superficial mycosis in the Northeastern China during 10 years

Abstract

This study analyzed the infection of superficial mycosis and the relationship between the distribution characteristics of pathogenic fungi and age, time and sex in Northeast China in the past 10 years. We would like to provide a theoretical basis for the diagnosis and treatment of related diseases. From December 2008 to December 2018, 5,374 superficial mycoses from Northeast China were selected. The fungal species were identified by fungal microscopy, fungal culture, and species identification. Besides, the relationship between sex, age, time and the distribution of superficial mycosis and pathogenic fungi was analyzed. Among the 5,374 patients, the top three infections were tinea pedis (n=1,538, 28.62%), tinea cruris (n=1,018, 18.94%) and tinea corporis (n=938, 17.45%). The top three pathogens were Trichophyton rubrum (n=2,849, 48.65%), Trichophyton mentagrophytes (n=947, 16.14%) and Candida spp. (n=804, 13.70%). The main pathogenic fungi were dermatophytes. The age group with the highest incidence of tinea capitis was children (n=372, 6.92%). The highest incidence rate of tinea pedis was in 31-69-year adults (n=905, 16.84%); Malassezia mainly affects young people aged 15-30. Yeast and mold mostly invade the elderly patients >60 years old. The incidence of tinea cruris, tinea pedis and tinea corporis in male patients was higher than that in female patients. The incidence of onychomycosis in female patients was higher than that in male patients (P<0.05). The isolation rate of Candida, Mold, Microsporum canis, Malassezia and Sporothrix increased year by year, while that of Trichophyton rubrum, Trichophyton mentagrophyte, Trichophyton schoenleinii and Epidermophyton floccosum decreased. From December 2008 to December 2018, dermatophytes were the main pathogens of superficial mycosis in Northeast China. The distribution of disease species and pathogenic fungi varied in different gender, age and time.

Prevalence of superficial‐cutaneous fungal infections in Shiraz, Iran: A five‐year retrospective study (2015–2019)

“…We reported that dermatophytosis was the second common type of SFI (34.8%), which is in line with previous studies 7 . However, in epidemiologic studies in China, Turkey, and Germany, 82%, 74%, and 83.2% of dermatophytosis were reported, respectively 26,28,31 . In this study, the nails were the most affected anatomic site in the patients, as similarly reported in Egypt and Southern China 18,27 .…”

Progress of polymer-based strategies in fungal disease management: Designed for different roles

“…Other classification systems, based on phenotypes, genetic relationships, and molecular criteria, are more complicated and less used in the clinical setting ( Gnat et al., 2019 ). Apart from dermatophytes, yeasts and molds have also been shown to cause superficial mycosis, with the elderly reportedly more susceptible to these less common pathogens than the younger population ( Wang et al., 2020b ). A summary of typical development of skin infections is shown in Table 1 .…”

Potential of orchid as antifungal agent resources: a scoping review

“…4 Incidence of fungal infection diseases is higher in men compared to a woman. 5 Fungal infection disease can be classified into two groups, superficial infection and systemic infection. 6 Superficial fungal infection is a fungal infection that affects the surface of the body such as skin, hair, and nails.…”

“…(17.40%). 5 The most frequent infection sites of T. rubrum include foot, inguinal, axilla, scalp, and nail. This infection causes mild to moderate dermatological symptoms with a variety of severity.…”