Analytical Conditions and Separation Performance of Capillary Chromatography Based on the Tube Radial Distribution of Aqueous-Organic Mixture Carrier Solvents under Laminar-Flow Conditions

Consideration of the Tube Radial Distribution of the Carrier Solvents in a Capillary Tube under Laminar Flow Conditions and Computer Simulation

“…13 In this paper, the formation of inner and outer phases in the TRDP is considered based on experimental data that were reported in our previous papers. [7][8][9][10] Also, the results of computer simulations agree well with the phase formation observed through the TRDP.…”

“…That is, the TRDP is a new phase interface concept, and can be applied to various technological, engineering, and scientific fields. We are currently investigating the TRDP from the viewpoints of chromatography, 10,11 extraction, 12 and chemical reaction space. 13 In this paper, the formation of inner and outer phases in the TRDP is considered based on experimental data that were reported in our previous papers.…”

An Abnormal Temperature Dependence of Alkylpyrazines’ Retention in Reversed-Phase Liquid Chromatography

“…With ACN as a component of the mobile phase, all the retention factors for these alkylpyrazines were increasing when the column temperature was elevated, suggesting an abnormal temperature-dependence of the retention factor as found in other previous reports. 18,19 On the contrary, when the column temperature was elevated with MeOH-based mobile phases, all the retention factors were gradually decreased, as normally found in typical RPLC separation conditions. [20][21][22][23][24] Similar trends were also observed for all other alkyl-bonded stationary phases employed in this work.…”

Experimental Consideration of Capillary Chromatography Based on Tube Radial Distribution of Ternary Mixture Carrier Solvents under Laminar Flow Conditions

“…[16][17][18] That is, in the case of a water-rich carrier solution, the hydrophilic analyte, which is dispersed in the water-rich major phase (around the middle of the capillary tube), is eluted with nearly average linear velocity. The hydrophobic analyte, which is dispersed in the organic solvent-rich minor phase near the inner wall of the tube (pseudo-stationary phase), is eluted with a lower velocity than the average linear velocity.…”

“…[13][14][15] Recently, it was proposed that, when the ternary solvent mixture of water-hydrophilic/hydrophobic organic solvent is fed into capillary tubes under laminar flow conditions, the mixture solvents are radially distributed in the capillary tubes. [16][17][18] The phenomenon of the tube radial distribution of the ternary mixture solvents in a capillary tube under laminar flow conditions will be referred to as "tube radial distribution phenomenon (TRDP)" for convenience.…”