Anatomical and physiologic assessments in patients with small coronary artery disease: Final results of the Physiologic and Anatomical Evaluation Prior to and After Stent Implantation in Small Coronary Vessels (PHANTOM) trial

Costa, Marco A.; Sabaté, Manel; Staico, Rodolfo; Alfonso, Fernándo; Seixas, Ana C.; Albertal, Mariano; Crossman, Arthur W.; Angiolillo, Dominick J.; Zenni, Martin M.; Sousa, J. Eduardo; Macaya, Carlos; Bass, Theodore A.

doi:10.1016/j.ahj.2006.10.036

Cited by 54 publications

(52 citation statements)

References 21 publications

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“…For any prediction study, the number of "events" is critical, but only 49 of 236 lesions (21%) in the current study 1 had an FFR Ͻ0.8. This contrasts to 63% in FAME 2 but is similar to the positive FFR rates in prior work comparing IVUS against FFR: 25 of 51 (49%) lesions, 18 12 of 53 (23%) lesions, 19 14 of 55 (25%) patients, 20 19 of 56 (34%) patients, 21 and 38 of 94 (40%) patients. 22 Although the majority of patients in the most recent study 1 underwent PCI for stable angina, data on pre-PCI stress testing are not provided.…”

Section: Article See P 65contrasting

confidence: 39%

Don't Judge a Book by Its Cover

Johnson

Davidson

2011

Circ: Cardiovascular Interventions

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Section: Article See P 65contrasting

confidence: 39%

Don't Judge a Book by Its Cover

Johnson

Davidson

2011

Circ: Cardiovascular Interventions

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“…Because PCI of nonsignificant lesions does not decrease major adverse events or improve symptoms [39,40] functional tests should be used to decide whether PCI is warranted for angiographically stable, intermediate severity (50-70%) lesions. Although most 50% stenoses by angiography are not functionally significant, several factors (eccentricity, length, or presence of serial lesions) can render a 50% stenosis hemodynamically significant [41][42][43][44].…”

Section: Methods Of Determining Significance Of Coronary Diseasementioning

confidence: 99%

“…For patients with an FFR between 0.75 and 0.80, angina at follow-up was less prevalent in those who underwent PCI compared with those treated conservatively [50]. An FFR of >0.75 or >0.80 correlates with excellent long-term outcomes if PCI is deferred [40,43,[51][52][53]. FFR has also been shown to predict physiologic significance of left main coronary lesions, although the data are not as robust [54][55][56].…”

Section: Methods Of Determining Significance Of Coronary Diseasementioning

confidence: 99%

Staging of multivessel percutaneous coronary interventions: An expert consensus statement from the Society for Cardiovascular Angiography and Interventions

Blankenship

Moussa

Chambers

et al. 2011

Cathet Cardio Intervent

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Percutaneous coronary interventions (PCIs) to treat multivessel coronary artery disease (MVCAD) may involve single-vessel or multivessel interventions, performed in one or more stages. This consensus statement reviews factors that may influence choice of strategy and includes six recommendations to guide decisions regarding staging of PCI [1]. Every patient who undergoes PCI should receive optimal therapy for coronary disease, ideally before starting the procedure [2]. Multivessel PCI at the time of diagnostic catheterization should be considered only if informed consent included the risks and benefits of multivessel PCI and the risks and benefits of alternative treatments [3]. When considering multivessel PCI, the interventionist should develop a strategy regarding which stenoses to treat or evaluate, and their order, method, and timing. This strategy should maximize patient benefits, minimize patient risk, and consider the factors described in this article [4]. For planned multivessel PCI, additional vessel(s) should be treated only if the first vessel is treated successfully and if anticipated contrast and radiation doses and patient and operator conditions are favorable [5]. After the first stage of the planned multistage PCI, the need for subsequent PCI should be reviewed before it is performed [6]. Third party payers and quality auditors should recognize that multistage PCI for MVCAD is neither an indication of poor quality nor an attempt to increase reimbursement when performed according to recommendations in this article.V C 2011 Wiley Periodicals, Inc.

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“…There have been previous comparative studies showing good to excellent correlation between CCTA and IVUS geometrical parameters (52). This has led to the use of CCTA to prospectively evaluate changes in IVUS-like parameters such as MLA (53).…”

Section: Intravascular Coronary Imaging and Its Relation With Functiomentioning

confidence: 99%

Impact of plaque characteristics on the degree of functional stenosis

Gonçalves

Hideo‐Kajita

García‐García

2017

Cardiovasc. Diagn. Ther.

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Coronary CT angiography (CCTA) is mainly regarded as a gatekeeper for invasive coronary angiography, in face of its widely recognized value to noninvasively rule out significant coronary stenosis. Nevertheless, it is also increasingly recognized that this noninvasive modality can depict several atherosclerotic plaque features and quantify total coronary plaque burden. This opens a new field for cardiac CT, since these atherosclerotic features beyond stenosis severity have been correlated with the degree of functional significance, and are the focus of the present manuscript. Although recently acknowledged and documented in CCTA studies, the relation between plaque burden and functional significance has been previously described using several intracoronary imaging modalities, which are also reviewed in the manuscript, to help put in perspective the relation between anatomy and function in coronary artery disease.

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Anatomical and physiologic assessments in patients with small coronary artery disease: Final results of the Physiologic and Anatomical Evaluation Prior to and After Stent Implantation in Small Coronary Vessels (PHANTOM) trial

Cited by 54 publications

References 21 publications

Don't Judge a Book by Its Cover

Don't Judge a Book by Its Cover

Staging of multivessel percutaneous coronary interventions: An expert consensus statement from the Society for Cardiovascular Angiography and Interventions

Impact of plaque characteristics on the degree of functional stenosis

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