“…Against this backdrop of enthusiasm about the technical ease, potential safety and clinical utility of the TPSBs, and the uncertainty about their mechanism of action, 2 anatomic fascial planes in the posterior thorax 7,21,22,37,41 are rarely referred to in the TPSB literature but are noteworthy. They are the “intermuscular fat-filled fascial compartments” between the thoracic paraspinal muscles 7,31 and the “retro-SCTL space.” 21,22,37,41 These 2 anatomic spaces are interconnected, 21,22,31,41 and there is growing evidence 21,22,41 that they act as conduits for the physical spread of LA from the retro-SCTL space to the TPVS, intervertebral foramen, ES, and ICS after the TPSBs, 22,37,41 and thus warrants discussion.…”