Anatomy-corresponding method of IMRT verification

Winiecki, Janusz; Żurawski, Zbigniew; Drzewiecka, B.; Ślosarek, Krzysztof

doi:10.1016/j.rpor.2010.11.001

Cited by 8 publications

(8 citation statements)

References 10 publications

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“…found out that IMRT dose planed provide more uniform coverage of the PTV than 3D-CRT and IMRT resulted in a significant reduction of mean and/or maximum doses to OAR; of particular note, these authors reported that the mean dose to the parotid glands decreased by a mean of 13.5 Gy with the use of IMRT vs. 3D-CRT 29. The revealed differences in dose parameters between evaluated techniques were small due to the improvement in optimization applied in all radiotherapy techniques, thus detection tools and methods that allowed to trace the differences had to be appropriately accurate 12,30,31…”

Section: Discussionmentioning

confidence: 99%

Doses in organs at risk during head and neck radiotherapy using IMRT and 3D-CRT

Peszyńska-Piorun¹,

Malicki²

2012

Radiology and Oncology

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Background.Treatment planning for head and neck (H&N) cancer is complex due to the number of organs at risk (OAR) located near the planning treatment volume (PTV). Distant OAR must also be taken into consideration. Intensity-modulated radiotherapy (IMRT) and three-dimensional conformal radiotherapy (3D-CRT) are both common H&N treatment techniques with very different planning approaches. Although IMRT allows a better dose conformity in PTV, there is much less evidence as to which technique less dose to OAR is delivered. Therefore, the aim of the study was to compare IMRT to 3D-CRT treatment in terms of dose distribution to OAR in H&N cancer.Patients and methods.This was a prospective study of a series of 25 patients diagnosed with stage cT3–4N0–2 laryngeal cancer. All patients underwent total laryngectomy and bilateral selective neck dissections. In all cases, patients were treated with IMRT, although a 3D-CRT treatment plan was also developed for the comparative analysis. To compare doses to specific OAR, we developed a new comparative index based on sub-volumes.Results.In general, IMRT appears to deliver comparable or greater doses to OAR, although the only significant differences were found in the cerebellum, in which 3D-CRT was found to better spare the organ.Conclusions.Organs located outside of the IMRT beam (i.e., distant organs) are generally thought to be well-spared. However, the results of this study show that, in the case of the cerebellum, this was not true. This finding suggests that larger studies should be performed to understand the effects of IMRT on distant tissues. Anthropomorphic phantom studies could also confirm these results.

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Section: Discussionmentioning

confidence: 99%

Doses in organs at risk during head and neck radiotherapy using IMRT and 3D-CRT

Peszyńska-Piorun¹,

Malicki²

2012

Radiology and Oncology

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“…Hyperfractionation of RT dose and modern RT techniques with increased dose conformity ( e.g . intensity-modulated RT with image guidance) can further reduce the risk of optic neuropathy 23,24. Because only two cases with neck metastases of benign-appearing IPs have been reported so far7,25, no elective irradiation of regional lymphatics is needed.…”

Section: Discussionmentioning

confidence: 99%

Radiotherapy for inverted papilloma: a case report and review of the literature

Strojan¹,

Jereb²,

Borsos³

et al. 2013

Radiology and Oncology

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BackgroundSinonasal inverted papilloma (IP) is a rare, usually benign tumor arising from the respiratory mucosa of the sinonasal tract. Surgical resection is the treatment of choice. In histologically overt benign IPs (i.e. without associated malignancy) irradiation was employed only anecdotally. The patient with gross residual of benign IP after up-front surgery that was subsequently treated with irradiation is presented and the literature reports on the use of radiotherapy (RT) in this tumor type are reviewed.Case reportAfter the surgical treatment the residuum in the region of the sphenoid and adjacent cavernous sinus was irradiated to 54 Gy in 1.8 Gy daily fractions. No recurrence or deterioration of olfaction, hearing or vision was observed 2.6 years post-RT.Review of the literatureIn the literature, six reports were identified with 16 patients describing necessary details on RT and outcome. Twelve of 14 cases (our case included) with gross or subtotal tumor resection and postoperative RT were locally controlled. The lowest and the median irradiation doses were 47.15 Gy and 56.5 Gy, respectively, and the follow-up period ranged between 0.5–20.5 years (median 7.8 years).ConclusionsRT is safe and valuable treatment option in histologically overt benign IPs. It is indicated when the risk of tumor recurrence after surgery is increased and in inoperable tumors.

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“…Anatomy corresponding method. This method was proposed to link gamma information to patient anatomy [30]. To overcome the absence of regional information in simple gamma analysis, the authors suggested a method that cross-examines gamma results on patient's digital reconstructed radiographs (DRRs).…”

Section: Biological-anatomy Related Methodsmentioning

confidence: 99%

Treatment plan verification: A review on the comparison of dose distributions

et al. 2019

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The aim of this review article is to provide a useful reference for dose comparison techniques within the frame of treatment plan verification. Each technique is presented with a general description given along with advantages and disadvantage and the rationale for its development. Methods: The review was conducted in PubMed from 1993 to 2019 including articles referring to the methodology of dose comparison for treatment plan verification. Results: The search identified thirty-one dose comparison methods that were categorized according to the number of physical parameters that take into account for dose comparison. Conclusions: Among the available methods for the comparison of two dose distributions, the γ-analysis (gamma analysis) has been widely adopted as the gold standard in verification procedures. However, due to various intrinsic limitations of gamma index, the development of a better metric taking into account both statistical and in clinical parameters is required.

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Anatomy-corresponding method of IMRT verification

Abstract: It seems, that the complex monitoring of treatment would be possible owing to the images obtained as a cross-examination of γ-images and corresponding DRRs.

Cited by 8 publications

References 10 publications

Doses in organs at risk during head and neck radiotherapy using IMRT and 3D-CRT

Doses in organs at risk during head and neck radiotherapy using IMRT and 3D-CRT

Radiotherapy for inverted papilloma: a case report and review of the literature

Treatment plan verification: A review on the comparison of dose distributions

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