Androgen Receptor (AR) and Breast Cancer: Reference to the AR Status in Normal/Benign Breast Luminal Cells

Abstract

The role of androgen and androgen receptor pathway in breast cancer development, prognosis and treatment has gained enormous attentions in recent years, largely because of the effort to identify new markers for targeted treatment of triple (ER/PR/Her2) negative breast carcinomas. This mini-review will discuss AR and breast cancer from the perspectives of normal/benign breast luminal epithelium.