2000
DOI: 10.1590/s0103-84782000000400013
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Anestesia geral com propofol em cães pré-tratados com acepromazina e alfentanil

Abstract: RESUMO Foram utilizados 30 cães, sem raça definida, adultos, (10 machos e 20 fêmeas), com peso médio de 14,44 ± 2,72kg, distribuídos em três grupos. O grupo I (GI) recebeu

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Cited by 6 publications
(14 citation statements)
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“…Reduction in the mean arterial blood pressure was observed by Ferro et al (2005) and Cortopassi et al (2000), suggesting that depression was probably caused by propofol acting on vasomotor centers located in the brain stem, resulting in the combination of a reduced cardiac output and systemic vascular resistance, and possibly by the combination with other drugs (acepromazine in this case). Changes in blood pressure were not observed by Pereira et al (2013), by implementing doses of 0.3 mg kg -1 of methadone, intramuscularly and intravenously in dogs.…”
Section: Resultssupporting
confidence: 52%
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“…Reduction in the mean arterial blood pressure was observed by Ferro et al (2005) and Cortopassi et al (2000), suggesting that depression was probably caused by propofol acting on vasomotor centers located in the brain stem, resulting in the combination of a reduced cardiac output and systemic vascular resistance, and possibly by the combination with other drugs (acepromazine in this case). Changes in blood pressure were not observed by Pereira et al (2013), by implementing doses of 0.3 mg kg -1 of methadone, intramuscularly and intravenously in dogs.…”
Section: Resultssupporting
confidence: 52%
“…Cortopassi et al (2000) found an increase in PaCO 2 due to alfentanil administration that remained higher after the application of propofol. Therefore, it can be presumed that the increase in ETCO 2 in this study may have been caused by the association of opioid drugs with the depressant effect of propofol on respiratory function.…”
Section: Resultsmentioning
confidence: 87%
“…Assim como em humanos, os animais são classificados com a faixa etária. Pacientes neonatos são aqueles que possuem até dois semanas de vida, filhotes de duas a seis semanas, pediátricos de 6 a 12 semanas e fase juvenil compreende os animais de três a seis meses de idade (Cortopassi & Carvalho, 2010). Quando procedimentos cirúrgicos são necessários em pacientes pediátricos, e consequentemente de anestesia para aliviar dor e desconforto, é crucial lembrar que o desenvolvimento e a maturação de órgãos não seguem o mesmo padrão que ocorre em animais adultos (Domeneghetti et al, 2015;Fantoni & Cortopassi, 2009).…”
Section: Pubvetunclassified
“…Nestes pacientes, o metabolismo de fármacos é reduzido devido maior proporção de água corporal e menor concentração de proteínas. Isso pode resultar em uma eliminação farmacológica menos eficaz, levando a uma maior concentração de anestésicos no plasma e, potencialmente, causando intoxicação (Cortopassi & Carvalho, 2010;Scarparo et al, 2020). Além disso, os pacientes jovens possuem pouco tecido adiposo, o qual desempenha um papel fundamental no controle da temperatura corporal.…”
Section: Pubvetunclassified
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