“…While the HMEF is intended for single use only, BCS can either be single used or reused. The filtration efficacy and safety of HMEF are well studied [1], [2], [3], however, there is still limited clinical evidence on the optimal duration for prolonged BCS usage when used for more than 24 hours in operating room settings [4], [5], [6], [7], [8]. Existing recommendations differ, e.g.…”