Anesthetic Implications in Managing a Case of Primary Hyperaldosteronism: A Case Report

Abstract

Primary hyperaldosteronism (also called Conn's syndrome) is a rare condition of the adrenal glands characterized by excessive secretion of the hormone aldosterone, which regulates the balance of water and electrolytes in the body, and maintains blood volume and pressure. Hyperaldosteronism causes sodium and water retention, hypokalemia, hypertension, and muscle weakness. Common cause of primary hyperaldosteronism is an adrenal adenoma or bilateral adrenal hyperplasia. A 36-year-old female presented with hypertension, hypokalemia and muscle cramps, and on further evaluation by computed tomography (CT) scan was found to have a right adrenal adenoma. She was scheduled for a right-sided laparoscopic adrenalectomy. We report the successful peri-operative anesthetic management of this patient who had an uneventful intra-operative and post-operative course.

The causal association between primary aldosteronism and cardiovascular diseases: a bidirectional two-sample Mendelian randomization study

“…The adrenal disease characterized by excessive secretion of aldosterone is called hyperaldosteronism and can be divided into primary (also called Conn's syndrome or PA) and secondary forms [36,37]. Pathologically, on the one hand, aldosterone promotes stimulating in ammatory cell in ltration, oxidative stress, and endothelial damage.…”