1987
DOI: 10.1016/s0190-9622(87)70161-3
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Angiogenesis and the skin

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Cited by 39 publications
(12 citation statements)
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“…For new blood vessel formation in adults from preexisting blood vessels, increase in vascular permeability and vasodilatation often result in signals that induce angiogenesis. Subsequently, endothelial cells enlarge, form pseudo pods and producing a variety of proteases capable of degrading basement membrane proteins, they can migrate, and form vascular sprouts [30][31][32].…”
Section: Discussionmentioning
confidence: 99%
“…For new blood vessel formation in adults from preexisting blood vessels, increase in vascular permeability and vasodilatation often result in signals that induce angiogenesis. Subsequently, endothelial cells enlarge, form pseudo pods and producing a variety of proteases capable of degrading basement membrane proteins, they can migrate, and form vascular sprouts [30][31][32].…”
Section: Discussionmentioning
confidence: 99%
“…Los resultados obtenidos en dichos estudios indican que la capacidad de inducción de angiogénesis es adquirida por los melanomas al pasar de fase radial a fase vertical y, por tanto, que el desarrollo de dicha capacidad puede ser un paso decisivo en la adquisición del fenotipo metastásico en el melanoma maligno cutáneo(l13, 114,115,116,117,118,119,120,121,122,123,124,125) Según algunos autores la célula característica del melanoma pueden producir, gránulos acumulados en su citoplasma, y secretar varios factores angiogénicos y factores de crecimiento que faciliten la neovascularización, incluyendo histamina, heparina, y factor de necrosis tumoral alfa. Otros investigadores demostraron que además estas células pueden producir y secretar el factor de permeabilidad vascular / factor de crecimiento endotelial vascular, que parece ser uno de los factores angiogénicos más importante.…”
Section: Angiogénesis En El Melanoma Cutáneounclassified
“…8 Spider angiomas occur between the second and ®fth months of pregnancy in 67% of white women and 11% of black women, 1,22,32 with 75% regressing within three months postpartum. 33 Clinically, they present on the neck, throat, face (especially around the eyes), and arms. They are characterized by a central erythematous punctum surrounded by ®ne radiating vessels and erythema.…”
Section: Vascular and Hematologic Changesmentioning
confidence: 99%