2021
DOI: 10.1016/j.jdiacomp.2021.108001
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Angiogenic potential of mesenchymal stem cells derived from patients with diabetes seeded on decellularized micro fragments

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Cited by 2 publications
(2 citation statements)
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“…They then transplanted the acellular micro-fragment from the bone marrow of an elderly diabetic patient suffering from lower extremity arterial disease and DFU. They found that the MSCs expressed and secreted angiogenic factors similar to those extracted from healthy individuals ( 153 ). This provides a good idea for researching and developing stem cells and scaffolds.…”
Section: Mscs and Stem Cellsmentioning
confidence: 99%
“…They then transplanted the acellular micro-fragment from the bone marrow of an elderly diabetic patient suffering from lower extremity arterial disease and DFU. They found that the MSCs expressed and secreted angiogenic factors similar to those extracted from healthy individuals ( 153 ). This provides a good idea for researching and developing stem cells and scaffolds.…”
Section: Mscs and Stem Cellsmentioning
confidence: 99%
“…Decreased viability of stem cells due to late glycosylation end products in a hyperglycemic environment diminishes the efficacy of stem cells in enhancing wound healing in DFUs [ 65 ]. However, a study by Assis et al [ 66 ] reported that the MSCs from diabetic patients have the same potential for angiogenesis if they are seeded on decellularized micro fragments. The MSCs were isolated from the bone marrow of distal tibial or femoral shafts from the amputated limb.…”
Section: Limitations and Future Perspectivesmentioning
confidence: 99%