Angiographic Profile and Treadmill Test Relationship of Women with Chest Pain Suggestive of Coronary Artery Disease

George, Stanley

doi:10.4236/wjcd.2017.78021

Cited by 2 publications

(1 citation statement)

References 14 publications

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“…Periyapattana and AVS from south India and Stanley suggested in their study that combined TMT and MPI in-creases the PPV to 94% and diagnostic accuracy to 88% and together performs the gatekeeper function for CAG so that optimal decision making can be achieved. 8,9 Our study showed that PPV of TMT is lower (53%) in females than in males (83%). To detect obstructive CAD by CAG, better to see the other parameters also such as age and diabetes along with high-probability TMT.…”

Section: Discussionmentioning

confidence: 54%

Correlation of Treadmill Stress Test with Coronary Angiography to Predict Coronary Artery Disease in Males versus Females

Kumar

Bhuvaneshwari

2017

Ind J Car Dis Wom

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IntroductionIn the emerging health care scenario in developing countries, urbanized lifestyle changes are resulting in increased prevalence of cardiovascular risk factors (diabetes, obesity, hypertension [HTN], and hypercholesterolemia). These in turn result in cardiovascular diseases (CVDs) that include coronary heart disease and stroke. The accuracy of the treadmill stress test (TMT) in predicting significant coronary heart disease is variable, depending Keywords ► coronary artery disease ► coronary angiography ► treadmill stress test AbstractBackground Treadmill stress test (TMT) is the most commonly performed stress test for diagnosis of coronary artery disease (CAD) in outpatient setting. The present study was conducted to find correlation of TMT with coronary angiography (CAG) in males versus female patients. Methods Total 422 patients who had undergone CAG and TMT were enrolled in present study. TMT test was done using Bruce protocol, and results were classified as inconclusive, low, intermediate, and high probability for inducible ischemia. Results Of 422 patients enrolled in the present study, 290 (69%) were males and 132 (31%) were females. Clinical presentation was angina on exertion CCS class II-III in 302 (71.6%) patients and angina equivalent in 124 (29.4%) patients. Out of these, 211 (50.2%) were diabetic and 308 (72.9%) were hypertensive. TMT was inconclusive, low, intermediate, and high probability for inducible ischemia in 35 (8.2%), 40 (9.7%), 19 (4.5%), and 328 (77.7%) patients, respectively. CAGs were normal in 149 (35.4%) patients and abnormal in 273 (64.6%) patients. Out of 328 patients with strongly positive TMT, 104 (31.7%) had normal coronaries, 56 (17%) had mild CAD, while 75 (22.8%) had SVD. LMCA disease, DVD, and TVD were found in 5 (1.5%), 48 (14.6%), and 40 (12.1%) patients, respectively. Of 132 female patients, 70 (53%) were found to have CAD and 62 (47%) had normal coronaries on CAG. Of 290 males, 241(83.1%) were found to have CAD and 49 (16.8%) had normal coronaries on CAG. Positive predictive value (PPV) in females was 53% and in males was 83%. Subgroup analysis showed that if there was high-probability TMT along with older age (p < 0.00), male sex (p < 0.01), and diabetes (p < 0.00), chances of having CAD were more. Conclusion PPV of positive TMT in female is 53% and in male is 83%. High-probability TMT along with the older age, male sex, and presence of diabetes mellitus (DM) makes the probability of having CAD is high.

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Section: Discussionmentioning

confidence: 54%

Correlation of Treadmill Stress Test with Coronary Angiography to Predict Coronary Artery Disease in Males versus Females

Kumar

Bhuvaneshwari

2017

Ind J Car Dis Wom

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Comparison of Epicardium Adipose Tissue Thickness in Treadmill Test Positive and Negative Patient

SURYADEEP GUPTA,

GOVIND KOURETI,

YOGENDRA SINGH GOND

et al. 2024

Asian J Pharm Clin Res

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Objective: The objectives of this study were as follows: (1) To find out the relationship between the epicardial adipose tissue (EAT) thickness and the treadmill (TMT) test results. (2) To find out the correlation between the EAT thickness and waist circumference and serum low-density lipoprotein-cholesterol. Methods: This study was conducted on 77 patients with complaints of chest pain and came for evaluation to our institution during the study period. All the patients were explained about the study, transthoracic echocardiography, and about EAT as newer cardiovascular risk factors. After obtaining their verbal consent to participate in the study, a voluntary written informed consent was obtained from the patient and/or his/her legally acceptable representative. Results: Majority of the patients were in the age group 41–50 years. Males (54.5%) were more in our study compared to the females. Out of the 77 patients with chest pain, who underwent TMT test, the test was positive in 50.6% patients, negative in 42.9% patients, and inconclusive in 6.5% patients. The comparison of fat pad thickness during the systole was found significantly higher in TMT-positive patients and lowest in the inconclusive patients (p<0.05). Conclusion: There was a significant relationship between the TMT results and the EAT thickness in our study. The thickness of EAT was highest in TMT-positive patients and lowest in the TMT inconclusive test result patients.

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Angiographic Profile and Treadmill Test Relationship of Women with Chest Pain Suggestive of Coronary Artery Disease

Cited by 2 publications

References 14 publications

Correlation of Treadmill Stress Test with Coronary Angiography to Predict Coronary Artery Disease in Males versus Females

Correlation of Treadmill Stress Test with Coronary Angiography to Predict Coronary Artery Disease in Males versus Females

Comparison of Epicardium Adipose Tissue Thickness in Treadmill Test Positive and Negative Patient

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