Angiomyxoma diagnosed in a man presenting for abdominal lipectomy

Abstract

Aggressive angiomyxoma is a rare tumour that is locally infiltrative but nonmetastasizing. It occurs nearly exclusively in adult women of childbearing age and almost always arises in the perineum and pelvic area. A case of angiomyxoma occurring in a middle-aged, morbidly obese man is reported. The clinical presentation was one of progressing scrotal edema and enlargement with subsequent development of scrotal abscesses, requiring several incisions and drainages as well as oral and intravenous antibiotics. His symptoms and body habitus left him in a significantly debilitated state, prompting him to seek treatment for his conditions. He initially presented for abdominal lipectomy. However, due to the chronic scrotal infections and enlargement, scrotectomy was recommended before any other surgical procedures. A scrotectomy was performed by the urology service. Pathological diagnosis of the excised tumour was an aggressive angiomyxoma. Given the rarity of this tumour, especially in males, the proper diagnosis and treatment of angiomyxoma is still being investigated. With this in mind, the physical signs and symptoms that characterize this condition are presented and treatment options are reviewed.

Massive recurring angiomyxoma of the scrotum in a obese man

“…3 AAM occurs almost exclusively in adult females, and, to our knowledge, only 43 cases occurring in men have been reported in the literature. 5 In men, AAM usually involves the scrotum (38%), spermatic cord (33%), perineal region (13%), and intrapelvic organs such as the bladder (8%).…”

“…AAM is a rare mesenchymal benign myxoid tumor, poorly circumscribed and characterized by locally infiltrative nature 1 and relatively rapid growth. 3 AAM occurs almost exclusively in adult females, and, to our knowledge, only 43 cases occurring in men have been reported in the literature. 5 In men, AAM usually involves the scrotum (38%), spermatic cord (33%), perineal region (13%), and intrapelvic organs such as the bladder (8%).…”

“… 1 This tumor, characterized by locally infiltrative nature and high recurrence rate (36–72%), 2 was given its name due to the pathological findings of stellate and spindled cells along with variable-sized blood vessels intricately entwined within a myxoid matrix. 3 AAM occurs almost exclusively in adult females, arising from the soft tissue of the pelvic region, perineum, vulva and buttock. 4 To our knowledge, only 43 cases occurring in men have been reported in the literature.…”

Aggressive angiomyxoma as a rare cause of scrotum enlargement in a 10-month-old boy: a case report

“…Aggressive angiomyxoma is a rare tumour that is locally infiltrative but non-metastasizing. It occurs nearly exclusively in adult women of childbearing age and almost always arises in the perineum and pelvic area [ 5 ], occurring only rarely in other sites, such as the vagina, urinary bladder, various cutaneous locations, soft tissue of the perineum and perianal region, or in the uterine cavity as a polyp [ 1 , 5 , 6 ]. In males, AAM involves analogous sites, usually the scrotum[ 7 , 8 ].…”

Angiomixoma Pélvico Asociado a Endometriosis Infiltrativa Profunda. Reporte de un caso

“…Destaca la ausencia de atipias y escas actividad mitótica, con preeminencia de células fusiformes y estrelladas. Pueden expresar receptores para estrógenos y progesterona, lo que se asocia con efectos hormonales en su crecimiento (Rotmensch et al, 1993;Idrees et al;Andres & Mishra, 2007;Chen et al, 2017).…”