Angiosarcoma characterized by colonic polyps

Abstract

Rationale: Angiosarcoma is a highly invasive tumour with a low incidence rate but high rates of local recurrence and distant metastasis and a poor prognosis. Understanding the endoscopic characteristics of angiosarcoma will help with early diagnosis and treatment of this disease. Patient concerns: The patient was a 77-year-old female who was admitted to the hospital due to recurring melena for 3 months. Outpatient gastroscopy showed that the patient had multiple gastric erosions. Colonoscopy revealed the presence of multiple protruding lesions in the colon and multiple rectal polyps. Pathological biopsy indicated that the patient had a tubular adenoma, which was removed by endoscopic resection. Diagnoses: Postsurgical pathologic assessment suggested that the histological subtype was epithelioid angiosarcoma. Positron emission tomography-computed tomography (PET-CT) revealed multiple metastases in the lymph nodes and bone. Interventions: The patient underwent acid suppression to protect the stomach, fluid supplementation and red blood cell infusion, and subsequently, surgery, radiotherapy and chemotherapy were recommended. The patient's family refused further treatments for the patient and requested discharge. Outcomes: The patient refused further treatment and was not followed-up. Lessons: Colorectal angiosarcoma is an extremely rare and highly malignant tumour, and understanding its endoscopic morphology will help aid in its diagnosis.

Multiple epithelioid angiosarcoma of stomach and small intestine with multiple lymph node metastases: A case report

“…[6][7][8][9][10] Because of the low incidence of gastrointestinal epithelioid angiosarcoma, the pathogenesis has not been clarified, but it may be related to foreign bodies, exogenous toxins and long-term exposure to vinyl chloride. [11] The disease can metastasize widely at early diagnosis, with poor healing and a median survival of 16 to 42 months. [6] We present a case of multiple epithelioid angiosarcoma of the gastrointestinal tract with lymph node metastasis.…”

Multiple epithelioid angiosarcoma of stomach and small intestine with multiple lymph node metastases: A case report

“…Five cases of primary gastric lesions and one case of multiple lesions in the stomach and small intestine have been reported [6][7][8][9][10] . Because of the low incidence of gastrointestinal epithelioid angiosarcoma, the pathogenesis has not been clari ed, but it may be related to foreign bodies, exogenous toxins and long-term exposure to vinyl chloride [11] . The disease can metastasize widely at early diagnosis, with poor healing and a median survival of 16-42 mo [6] .…”