Angiosarcoma of the Aorta

Epithelioid Angiosarcoma of the Aorta in a 47-Year-old Man: A Case Report and Literature Review

“…5,21 They may present either with or without an aortic aneurysm. 16,26 Thromboembolic metastases to the skin, 14 mesenteric vessels, 15 marginal arteries of small bowel, 27 distal peripheral vessels, 24 and brain 26 have been reported. The malignant nature of these thromboemboli is recognized during their pathologic evaluation after resection or biopsy.…”

“…The use of adjuvant therapy is at best uncertain. 16,34 Few randomized prospective trials evaluating soft tissue sarcomas have been performed, and these trials are further complicated by the mixed results with an insufficient follow-up period. Most such trails give mixed result with insufficient number of patients to draw a firm conclusion.…”

Predictors of survival in malignant aortic tumors

“…Table IV summarizes the median survival of different histologic subtypes. Nevertheless, some subtypes, such as leiomyosarcoma and hemangiosarcoma, showed longer median survival (12 [3-24] months and 12 [12][13][14][15][16][17][18][19][20][21][22][23][24] months, respectively) in comparison with other rarer types, such as fibrosarcoma and myxofibrosarcoma (Table IV). An early MAT diagnosis (before 11.5 weeks from symptom onset) was not associated with a significant survival rate improvement compared with patients diagnosed after 11.5 weeks (median survival, 19 months vs 15 [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] months; P ¼ .82).…”

Angiosarcome de l'aorte thoraco-abdominale avec hypertension artérielle, anémie et ischémie intestinale

“…Ces trois marqueurs ont et e identifi es dans la masse tumorale principale et dans les l esions m etastatiques dans notre observation. D'autres marqueurs histochimiques, tels que le S100, l'HMB45, l'actine et la desmine peuvent ê tre utilis es pour discriminer des cancers m etastatiques et les autres tumeurs aortiques primitives dans les cas difficiles 5 .…”

“…La r esection chirurgicale du segment d'aorte porteur de la tumeur avec mise en place d'une proth ese aortoaortique est le traitement de choix. On ne sait pas si la thromboendart eriectomie sans r esection aortique est un traitement ad equat dans la mesure où th eoriquement les cellules tumorales sont intimales et donc confin ees a la l esion intra-luminale 5,6,19 . Notre observation souligne la pr esentation clinique vari ee des angiosarcomes intimaux.…”