Animal Caliciviruses

Ghosh, Souvik; Malik, Yashpal Singh; Kobayashi, Nobumichi

doi:10.1007/978-981-15-2651-0_4

Cited by 2 publications

(7 citation statements)

References 116 publications

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“…Noroviruses are small, non-enveloped viruses of the Caliciviridae family. The name Caliciviridae derives from the Latin word calix and is due to the characteristic cup-shaped depression on the virion surface of all the family members [ 4 ].…”

Section: Resultsmentioning

confidence: 99%

“…The Calicivirus virion has a diameter of 27–40 nm, and the capsid is composed of 90 dimers of the single, major capsid protein (VP1), which are arranged in a T = 3 icosahedral symmetry [ 4 ]. The VP1 protein has a shell (S) domain, conserved and internal to the virion, and a protruding domain (P), variable and externally exposed.…”

Section: Resultsmentioning

confidence: 99%

“…This last domain is further composed of P1 and P2 subdomains. The hypervariable region present in P2, interacting with the receptors on the host cell’s surface, is particularly important for classifying the antigenic diversity of the members of this viral family [ 4 ]. The virions also contain a minor basic protein (VP2) associated with the VP1 S domain.…”

Section: Resultsmentioning

confidence: 99%

“…The virus translation and transcription mechanism occur in the cytoplasm. After uncoating and disassembly, the VPg-linked RNA acts as a messenger RNA (mRNA) for the initial round or translation [ 4 ]. VPg (NS5) works as a cap and mediates the translation of viral RNA into proteins using the host cell apparatus.…”

Section: Resultsmentioning

confidence: 99%

“…Viral replication occurs in close association with the rearrangement of intracellular membranes driven by viral proteins NS1/2 and NS4 [ 18 ]. Genome duplication occurs through the synthesis of an intermediate RNA negative sense, which serves as a template for the RNA-dependent RNA-polymerase (RdRp) that synthesises positive sense gRNA and sgRNA [ 4 ]. The mechanism of virus release is still unclear.…”

Section: Resultsmentioning

confidence: 99%

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Swine Norovirus: Past, Present, and Future

Cavicchio

Laconi

Piccirillo

et al. 2022

Viruses

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Norovirus, an ssRNA + virus of the family Caliciviridae, is a leading disease burden in humans worldwide, causing an estimated 600 million cases of acute gastroenteritis every year. Since the discovery of norovirus in the faeces of swine in Japan in the 1990s, swine norovirus has been reported in several countries on several continents. The identification of the human-associated GII.4 genotype in swine has raised questions about this animal species as a reservoir of norovirus with zoonotic potential, even if species-specific P-types are usually detected in swine. This review summarises the available data regarding the geographic distribution of norovirus in swine, the years of detection, the genotype characterisation, and the prevalence in specific production groups. Furthermore, we discuss the major bottlenecks for the detection and characterisation of swine noroviruses.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Swine Norovirus: Past, Present, and Future

Cavicchio

Laconi

Piccirillo

et al. 2022

Viruses

View full text Add to dashboard Cite

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Complete Genome Sequence, Molecular Characterization and Phylogenetic Relationships of a Temminck’s Stint Calicivirus: Evidence for a New Genus within Caliciviridae Family

et al. 2022

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Caliciviridae is a family of viral pathogens that naturally infects vertebrates, including humans, and causes a range of highly contagious infectious diseases. Caliciviruses are not well studied because of the lack of a universal approach to their cultivation; however, the development of molecular genetics and bioinformatics methods can shed light on their genetic architecture and evolutionary relationships. Here, we present and characterize the complete genome sequence of calicivirus isolated from a sandpiper—Temminck’s stint (Calidris temminckii), preliminarily named Temminck’s stint calicivirus (TsCV). Its genome is a linear, non-segmented, single-stranded (+sense) RNA with genome organization typical of avian caliciviruses. Comparative studies have shown significant divergence of the nucleotide sequence of the TsCV genome, as well as the amino acid sequence of the major capsid protein from all publicly available genomic and protein sequences, with the highest genome sequence similarity to unclassified Ruddy turnstone calicivirus A (43.68%) and the lowest pairwise divergence of the major capsid protein with unclassified goose calicivirus (57.44%). Phylogenetic analysis, as well as a comparative analysis of the homologous proteins, showed evidence of another separate genus within the Caliciviridae family—previously proposed, but not yet accepted by International Committee on Taxonomy of Viruses (ICTV)—the Sanovirus genus, which combines seven previously unclassified genomic sequences of avian caliciviruses, including the newly discovered TsCV, which we propose to consider as a separate species.

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Animal Caliciviruses

Cited by 2 publications

References 116 publications

Swine Norovirus: Past, Present, and Future

Swine Norovirus: Past, Present, and Future

Complete Genome Sequence, Molecular Characterization and Phylogenetic Relationships of a Temminck’s Stint Calicivirus: Evidence for a New Genus within Caliciviridae Family

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